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Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis

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dc.contributor.authorÂngelo Tavares Schwarzmeier, Lígia [UNESP]
dc.contributor.authorKitakawa, Dárcio
dc.contributor.authorEduardo Blumer Rosa, Luiz [UNESP]
dc.contributor.authorAntonio Guimarães Cabral, Luiz [UNESP]
dc.contributor.authorDias Almeida, Janete [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2020-12-12T01:47:29Z
dc.date.available2020-12-12T01:47:29Z
dc.date.issued2019-10-01
dc.description.abstractA nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity.en
dc.description.affiliationPaulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and Diagnosis
dc.description.affiliationUnespPaulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and Diagnosis
dc.format.extent569-572
dc.identifierhttp://dx.doi.org/10.14295/bds.2019.v22i4.1714
dc.identifier.citationBrazilian Dental Science, v. 22, n. 4, p. 569-572, 2019.
dc.identifier.dimensionspub.1122423075
dc.identifier.doi10.14295/bds.2019.v22i4.1714
dc.identifier.issn2178-6011
dc.identifier.issn1678-2046
dc.identifier.orcid0000-0002-4321-5306
dc.identifier.orcid0000-0001-9305-1891
dc.identifier.orcid0000-0003-4596-9715
dc.identifier.orcid0000-0001-7534-4674
dc.identifier.scopus2-s2.0-85075611330
dc.identifier.urihttp://hdl.handle.net/11449/199719
dc.language.isoeng
dc.publisherEditora Cubo
dc.relation.ispartofBrazilian Dental Science
dc.rights.accessRightsAcesso abertopt
dc.rights.sourceRightsoa_all
dc.rights.sourceRightsgold
dc.sourceScopus
dc.sourceDimensions
dc.subjectArthritis
dc.subjectGranuloma
dc.subjectJuvenile
dc.subjectLip
dc.subjectMethotrexate
dc.subjectPyogenic
dc.titleMethotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritisen
dc.titleMetotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenilept
dc.typeArtigopt
dspace.entity.typePublication
relation.isOrgUnitOfPublicationc73b286a-b5fa-4312-a7ec-62f987e7b514
relation.isOrgUnitOfPublication.latestForDiscoveryc73b286a-b5fa-4312-a7ec-62f987e7b514
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Ciência e Tecnologia, São José dos Campospt
unesp.departmentBiociências e Diagnóstico Bucal - ICTpt

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São José dos Campos - ICT - Instituto de Ciência e Tecnologia