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Ocular melanoma and mammary mucinous carcinoma in an African lion

dc.contributor.authorCagnini, Didier Quevedo [UNESP]
dc.contributor.authorSalgado, Breno S. [UNESP]
dc.contributor.authorLinardi, Juliana L. [UNESP]
dc.contributor.authorGrandi, Fabrizio [UNESP]
dc.contributor.authorRocha, Rafael M.
dc.contributor.authorRocha, Noeme Sousa [UNESP]
dc.contributor.authorTeixeira, Carlos Roberto [UNESP]
dc.contributor.authorDel Piero, Fabio
dc.contributor.authorSequeira, Julio Lopes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFEPI
dc.contributor.institutionPubl Vet Hosp
dc.contributor.institutionHosp AC Camargo Fundação Antonio Prudente
dc.contributor.institutionLouisiana State Univ
dc.date.accessioned2014-05-20T13:37:16Z
dc.date.available2014-05-20T13:37:16Z
dc.date.issued2012-09-25
dc.description.abstractBackground: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.Conclusions: This is the first description of these tumor in African lions.en
dc.description.affiliationUniv Estadual Paulista UNESP, Fac Med Vet & Zootecnia, Dept Clin Vet, Botucatu, SP, Brazil
dc.description.affiliationUniv Estadual Paulista UNESP, Fac Med Botucatu, Dept Patol, Botucatu, SP, Brazil
dc.description.affiliationFEPI, Curso Med Vet, Itajuba, Brazil
dc.description.affiliationPubl Vet Hosp, Dept Diagnost Pathol, Vet Serv, Natl Assoc Small Anim Clinicians Anclivepa, São Paulo, Brazil
dc.description.affiliationHosp AC Camargo Fundação Antonio Prudente, Dept Anat Patol, São Paulo, Brazil
dc.description.affiliationLouisiana State Univ, Sch Vet Med, Dept Pathobiol Sci, Baton Rouge, LA 70803 USA
dc.description.affiliationUnespUniv Estadual Paulista UNESP, Fac Med Vet & Zootecnia, Dept Clin Vet, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista UNESP, Fac Med Botucatu, Dept Patol, Botucatu, SP, Brazil
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdCNPq: 479178/2010-0
dc.description.sponsorshipIdFAPESP: 09/53493-9
dc.description.sponsorshipIdFAPESP: 10/51596-2
dc.description.sponsorshipIdFAPESP: 11/01610-1
dc.format.extent5
dc.identifierhttp://dx.doi.org/10.1186/1746-6148-8-176
dc.identifier.citationBmc Veterinary Research. London: Biomed Central Ltd., v. 8, p. 5, 2012.
dc.identifier.doi10.1186/1746-6148-8-176
dc.identifier.fileWOS000312222400001.pdf
dc.identifier.issn1746-6148
dc.identifier.lattes6077735918469284
dc.identifier.lattes8560913137958850
dc.identifier.lattes3409765424060945
dc.identifier.orcid0000-0002-8188-8149
dc.identifier.urihttp://hdl.handle.net/11449/12875
dc.identifier.wosWOS:000312222400001
dc.language.isoeng
dc.publisherBiomed Central Ltd.
dc.relation.ispartofBMC Veterinary Research
dc.relation.ispartofjcr1.958
dc.relation.ispartofsjr0,934
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectPanthera leoen
dc.subjectOcular neoplasmsen
dc.subjectMammary glanden
dc.subjectMelanocytic neoplasmsen
dc.subjectPeribiliary cystsen
dc.titleOcular melanoma and mammary mucinous carcinoma in an African lionen
dc.typeArtigo
dcterms.licensehttp://www.biomedcentral.com/about/license
dcterms.rightsHolderBiomed Central Ltd.
dspace.entity.typePublication
unesp.author.lattes6077735918469284[5]
unesp.author.lattes8560913137958850[7]
unesp.author.lattes3409765424060945
unesp.author.orcid0000-0002-8188-8149[5]
unesp.author.orcid0000-0001-6639-037X[7]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
unesp.departmentPatologia - FMBpt
unesp.departmentClínica Veterinária - FMVZpt

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