Publicação: Shvo's catalyst in chemoenzymatic dynamic kinetic resolution of amines-inner or outer sphere mechanism?
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
Evidence is provided for the inner-sphere mechanism with actual metal coordination of the racemic amine in the crucial hydrogen transfer step promoted by Shvo's catalyst of the chemoenzymatic dynamic kinetic resolution (DKR) of amines. Key intermediates involved in this H-transfer step were intercepted and continuously monitored by electrospray ionization mass spectrometry (ESI-MS) and characterized by their dissociation chemistries via ESI-MS/MS. © 2013 The Royal Society of Chemistry.
Descrição
Palavras-chave
Dissociation chemistry, Dynamic kinetic resolution, Electrospray ionization mass spectrometry, Hydrogen transfer, Innersphere mechanism, Metal coordination, Amines, Catalysts, Mass spectrometry, Dynamics
Idioma
Inglês
Como citar
Organic and Biomolecular Chemistry, v. 11, n. 39, p. 6695-6698, 2013.
