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Uranium deposition in bones of wistar rats associated with skeleton development

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dc.contributor.authorRodrigues, G.
dc.contributor.authorArruda-Neto, J. D T
dc.contributor.authorPereira, R. M R
dc.contributor.authorKleeb, S. R.
dc.contributor.authorGeraldo, L. P.
dc.contributor.authorPrimi, M. C.
dc.contributor.authorTakayama, L.
dc.contributor.authorRodrigues, T. E.
dc.contributor.authorCavalcante, G. T.
dc.contributor.authorGenofre, G. C.
dc.contributor.authorSemmler, R.
dc.contributor.authorNogueira, G. P. [UNESP]
dc.contributor.authorFontes, E. M.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionMethodist University
dc.contributor.institutionCEPESq/UniÍtalo-Italy-Brazilian University Center
dc.contributor.institutionUNIFEB-University Center
dc.contributor.institutionCatholic University of Santos/UNISANTOS
dc.contributor.institutionInstituto de Pesquisas Energéticas e Nucleares (IPEN)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:30:53Z
dc.date.available2014-05-27T11:30:53Z
dc.date.issued2013-12-01
dc.description.abstractSixty female Wistar rats were submitted to a daily intake of ration doped with uranium from weaning to adulthood. Uranium in bone was quantified by the SSNTD (solid state nuclear track detection) technique, and bone mineral density (BMD) analysis performed. Uranium concentration as a function of age exhibited a sharp rise during the first week of the experiment and a drastic drop of 70% in the following weeks. Data interpretation indicates that uranium mimics calcium. Results from BMD suggest that radiation emitted by the incorporated Uranium could induce death of bone cells. © 2013 Elsevier Ltd.en
dc.description.affiliationPhysics Institute University of São Paulo, São Paulo-SP
dc.description.affiliationVeterinary Medicine School Methodist University, São Paulo-SP
dc.description.affiliationCEPESq/UniÍtalo-Italy-Brazilian University Center, São Paulo SP
dc.description.affiliationSchool of Medicine University of São Paulo, São Paulo-SP
dc.description.affiliationMedical Physics School UNIFEB-University Center, Barretos-SP
dc.description.affiliationCatholic University of Santos/UNISANTOS, Santos-SP
dc.description.affiliationBiosciences Institute University of São Paulo, São Paulo-SP
dc.description.affiliationIPEN-Institute for Nuclear Energy Research, São Paulo-SP
dc.description.affiliationVeterinary Medicine School São Paulo State University/UNESP, Araçatuba-SP
dc.description.affiliationUnespVeterinary Medicine School São Paulo State University/UNESP, Araçatuba-SP
dc.format.extent105-110
dc.identifierhttp://dx.doi.org/10.1016/j.apradiso.2013.07.033
dc.identifier.citationApplied Radiation and Isotopes, v. 82, p. 105-110.
dc.identifier.doi10.1016/j.apradiso.2013.07.033
dc.identifier.issn0969-8043
dc.identifier.issn1872-9800
dc.identifier.scopus2-s2.0-84882942496
dc.identifier.urihttp://hdl.handle.net/11449/76912
dc.identifier.wosWOS:000328804000017
dc.language.isoeng
dc.relation.ispartofApplied Radiation and Isotopes
dc.relation.ispartofjcr1.123
dc.relation.ispartofsjr0,528
dc.rights.accessRightsAcesso restritopt
dc.sourceScopus
dc.subjectBone mineral density
dc.subjectRadiobiological effects
dc.subjectSkeleton bones
dc.subjectUranium incorporation
dc.subjectWistar rats
dc.subjectDaily intake
dc.subjectData interpretation
dc.subjectFemale Wistar rats
dc.subjectSolid-state nuclear track detections
dc.subjectUranium concentration
dc.subjectWistar rat
dc.subjectBone
dc.subjectData processing
dc.subjectMusculoskeletal system
dc.subjectUranium
dc.subjecturanyl nitrate
dc.subjectage
dc.subjectanimal experiment
dc.subjectanimal tissue
dc.subjectbioaccumulation
dc.subjectbone density
dc.subjectbone development
dc.subjectcontrolled study
dc.subjectfemale
dc.subjectfemur
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectquantitative analysis
dc.subjectrat
dc.subjectteratogenesis
dc.titleUranium deposition in bones of wistar rats associated with skeleton developmenten
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dspace.entity.typePublication
unesp.author.orcid0000-0001-7733-0153[11]
unesp.author.orcid0000-0002-3723-5028[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária, Araçatubapt

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Araçatuba - FMVA - Faculdade de Medicina Veterinária