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Paepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoids and naphthopyranone fractions

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dc.contributor.authorMoreira, Raquel Regina Duarte [UNESP]
dc.contributor.authorMartins, Gilmarcio Zimmermann [UNESP]
dc.contributor.authorPietro, Rosemeire Cristina Linhari Rodrigues [UNESP]
dc.contributor.authorSato, Daisy Nakamura [UNESP]
dc.contributor.authorPavan, Fernando Rogério [UNESP]
dc.contributor.authorLeite, Sergio R. A. [UNESP]
dc.contributor.authorVilegas, Wagner [UNESP]
dc.contributor.authorLeite, Clarice Queico Fujimura [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-05-15T13:30:32Z
dc.date.available2015-05-15T13:30:32Z
dc.date.issued2013
dc.description.abstractPaepalanthus spp., Eriocaulaceae, are native plants from Brazil known as “sempre-vivas” (everlasting flowers). In this work, we evaluated the potential anti-mycobacterial activity of two methoxylated flavonoids (flavonoid 7-methylquercetagetin and 7-methylquercetagetin-4′-O-β-D-glucopyranoside) isolated and identified from P. latipes and the naphthopyranone fractions from P. bromeliodes ethanolic extracts. The MIC value of 500 μg/mL was verified for all compounds tested against M. tuberculosis H37Rv. For M. avium, the MIC value ranged from 1000–2000 μg/mL excepting to naphthopyranone fractions with MIC of 500 μg/mL. This is the first report of activity determination of Paepalanthus spp. flavonoids activity against Mycobacterium tuberculosis and M. avium.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Campus do Litoral Paulista - Unidade São Vicente, São Vicente, Praça Infante Dom Henrique sn, Parque Bitarú, CEP 11330900, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Ciências Farmacêuticas, Departamento de Ciências Biológicas de Araraquara
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Instituto de Química de Araraquara
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP 2008/10390-2
dc.description.sponsorshipIdFAPESP 2011/11593-7
dc.format.extent268-272
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S0102695X13700358
dc.identifier.citationRevista Brasileira de Farmacognosia, v. 23, n. 2, p. 268-272, 2013.
dc.identifier.doi10.1590/s0102-695x2012005000137
dc.identifier.fileISSN0102-695X-2013-23-02-268-272.pdf
dc.identifier.issn0102-695X
dc.identifier.lattes7927877224326837
dc.identifier.lattes9818597076971227
dc.identifier.lattes2114570774349859
dc.identifier.lattes7710344461864924
dc.identifier.orcid0000-0003-3032-2556
dc.identifier.orcid0000-0002-4253-0320
dc.identifier.urihttp://hdl.handle.net/11449/123633
dc.language.isoeng
dc.relation.ispartofRevista Brasileira de Farmacognosia
dc.relation.ispartofjcr1.596
dc.rights.accessRightsAcesso abertopt
dc.sourceCurrículo Lattes
dc.subjectflavonoidsen
dc.subjectMycobacteriumen
dc.subjectnaphthopyranoneen
dc.subjectPaepalanthus sppen
dc.titlePaepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoids and naphthopyranone fractionsen
dc.typeArtigopt
dspace.entity.typePublication
relation.isDepartmentOfPublication5004bcab-94af-4939-b980-091ae9d0a19e
relation.isDepartmentOfPublication.latestForDiscovery5004bcab-94af-4939-b980-091ae9d0a19e
unesp.author.lattes7927877224326837
unesp.author.lattes9818597076971227
unesp.author.lattes2114570774349859
unesp.author.lattes7710344461864924[1]
unesp.author.orcid0000-0003-3032-2556[7]
unesp.author.orcid0000-0002-4253-0320[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, São Vicentept
unesp.departmentCiências Biológicas - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas