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First detection of the equine herpesvirus 1 neuropathogenic variant in Brazil

Abstract

This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G(2254)/D-752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A(2254)/N-752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.

Description

Keywords

Brazil, DNA polymerase gene, Equine herpesvirus 1, Neurological disease, Neuropathogenic

Language

English

Citation

Revue Scientifique Et Technique-office International Des Epizooties. Paris: Office Int Epizooties, v. 30, n. 3, p. 949-954, 2011.

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Item type:Unit,
Faculdade de Medicina Veterinária e Zootecnia
FMVZ
Campus: Botucatu


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