Jugular thrombophlebitis in horses: A review of fibrinolysis, thrombus formation, and clinical management

Martins Dias, Deborah Penteado [UNESP]; Lacerda Neto, Jose Correa de [UNESP]

Jugular thrombophlebitis in horses: A review of fibrinolysis, thrombus formation, and clinical management

Date

2013-01-01

Authors

Martins Dias, Deborah Penteado

Lacerda Neto, Jose Correa de

Publisher

Canadian Vet Med Assoc

Type

Article

Abstract

Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution and recanalization of the injured vessels. There are similarities between human and horse coagulation and flbrinolytic processes. This review examines the fibrinolytic system, thrombus formation, and the clinical management of jugular thrombophlebitis, including thrombolytic therapy. There is evidence that early regional thrombolytic therapy for jugular thrombophlebitis in horses may be effective to achieve sustained recanalization.