Quantitative aspects of the migration and evolutive asynchronism of Schistosoma mansoni in mice
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Abstract
Two groups of white mice (Mus musculus) were infected with 65 and 440 cercariae transcutaneously. Migration of Schistosoma mansoni from skin to the lungs and to the portal system thereafter was studied through fitting mathematical equations. Six evolutive stages previously defined were used to determine the asynchronic development of parasites in the portal system. Equations the moment of maximum schistosomula recovery in skin and lungs. In the portal system the equations lead to different days of maximum recovery according to each stage. These differences measure quantitatively the asynchronism of S. mansoni.
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Keywords
animal experiment, biological model, liver, migration, mouse, parasite ecology, schistosoma mansoni, trematode, Animal, Lung, Mice, Models, Biological, Portal System, Schistosoma mansoni, Schistosomiasis, Skin
Language
English
Citation
Revista do Instituto de Medicina Tropical de Sao Paulo, v. 20, n. 3, p. 121-132, 1978.
