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Long-term effects of imipramine on striatal dopamine autoreceptor function: Involvement of both noradrenergic and serotonergic systems

dc.contributor.authorScavone, Cristoforo
dc.contributor.authorAizenstein, Moacyr Luiz
dc.contributor.authorda Silva Planeta, Cleopatra
dc.contributor.authorde Lucia, Roberto
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T18:54:01Z
dc.date.available2022-04-28T18:54:01Z
dc.date.issued1992-01-01
dc.description.abstract1. 1. The effects of apomorphine (APO) administration on DA system activity were assessed by measuring dopamine metabolite levels (HVA) in several circumstances. 2. 2. Pretreatment with IMI reduced the effect of APO on HVA levels. 3. 3. Pretreatments with either IDE or DMI did not reduce the effect of APO on HVA levels. 4. 4. Reductions of either NE and 5-HT levels after DSP4 and pCPA restored the effect of APO after IMI pretreatment. © 1992.en
dc.description.affiliationLaboratório de Neuropsicofarmacologia, Departmento de Farmacologia, Instituto de Ciências Biomédicas da Universidade de São Paulo, Caixa Postal 4365, CEP 05508, São Paulo Brazil [Tel. 55-11-813-6944; Fax 55-11-813-0845]
dc.description.affiliationDepartmento de Princípios Ativos Naturais e Toxicologia, UNESP, Araquara, São Paulo, Brazil [Tel. 55-11-813-6944; Fax 55-11-813-0845]
dc.format.extent397-401
dc.identifierhttp://dx.doi.org/10.1016/0306-3623(92)90101-O
dc.identifier.citationGeneral Pharmacology, v. 23, n. 3, p. 397-401, 1992.
dc.identifier.doi10.1016/0306-3623(92)90101-O
dc.identifier.issn0306-3623
dc.identifier.scopus2-s2.0-0026598315
dc.identifier.urihttp://hdl.handle.net/11449/219151
dc.language.isoeng
dc.relation.ispartofGeneral Pharmacology
dc.sourceScopus
dc.titleLong-term effects of imipramine on striatal dopamine autoreceptor function: Involvement of both noradrenergic and serotonergic systemsen
dc.typeArtigo
dspace.entity.typePublication

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