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Populational influence on cephalometric landmark identification: performance of two AI-driven software programs in Brazilian and Korean images

dc.contributor.authorSilva, Thaisa Pinheiro
dc.contributor.authorPuntigam, Giovanna Sachs
dc.contributor.authorAndrade-Bortoletto, Maria Fernanda Silva
dc.contributor.authorTakeshita, Wilton Mitsunari [UNESP]
dc.contributor.authorOliveira-Santos, Christiano
dc.contributor.authorFreitas, Deborah Queiroz
dc.date.accessioned2026-04-09T20:30:46Z
dc.date.issued2025-10-10
dc.description.abstractObjectiveTo assess the performance of cephalometric landmark identification performed by two AI-driven software programs in images from different populations (Brazilian and Korean).MethodsSixty lateral cephalometric radiographs (30 Brazilian and 30 Korean) were analyzed. The Brazilian images were acquired using the Orthophos XG 5/Ceph device, while the Korean images were obtained from the International Symposium on Biomedical Imaging 2015 database. Images of patients with permanent dentition were included, excluding those with poor head positioning or severe craniofacial deformities. Twenty cephalometric landmarks were identified by two examiners used as the reference standard. Two AI-driven software programs, CefBot™ (Brazil) and WebCeph™ (Korea), automatically identified the same landmarks. Coordinate values for each landmark were measured using ImageJ, and the data were analyzed with Analysis of Variance and Dunnett’s post-hoc test.ResultsThe Brazilian software showed high accuracy in identifying landmarks on Brazilian images (90%) but was less precise on Korean images (80%), with significant discrepancies in the Glabella, Menton L, Basion, and Orbitale landmarks. Similarly, the Korean software had a higher accuracy in its own population (95%) than in another population (85%), with notable inaccuracies in the Menton L, Basion, and Porion landmarks.ConclusionDiscrepancies in the identification of specific landmarks, such as Glabella and Menton L, suggest that the accuracy of the software may be influenced by the training process itself and by the population origin of the training data.
dc.description.affiliationDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, 13414-903, Sao Paulo, Brazil
dc.description.affiliationDepartment of Oral Diagnosis, Division of Oral Radiology,, School of Dentistry of Araçatuba, Paulista State University (UNESP), Araçatuba, 16015-050, Sao Paulo, Brazil
dc.description.affiliationDepartment of Diagnosis and Oral Health, University of Louisville School of Dentistry, Louisville, KY, U.S.A.
dc.description.affiliationUnespDepartment of Oral Diagnosis, Division of Oral Radiology,, School of Dentistry of Araçatuba, Paulista State University (UNESP), Araçatuba, 16015-050, Sao Paulo, Brazil
dc.identifierhttps://app.dimensions.ai/details/publication/pub.1193792238
dc.identifier.dimensionspub.1193792238
dc.identifier.doi10.1186/s12903-025-06807-4
dc.identifier.issn1472-6831
dc.identifier.orcid0000-0002-7485-0206
dc.identifier.orcid0000-0001-5682-1498
dc.identifier.orcid0000-0001-9936-7547
dc.identifier.orcid0000-0002-1425-5966
dc.identifier.pmcidPMC12512714
dc.identifier.pmid41073937
dc.identifier.urihttps://hdl.handle.net/11449/321018
dc.publisherSpringer Nature
dc.relation.ispartofBMC Oral Health; n. 1; v. 25; p. 1596
dc.rights.accessRightsAcesso abertopt
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dc.titlePopulational influence on cephalometric landmark identification: performance of two AI-driven software programs in Brazilian and Korean images
dc.typeArtigopt
dspace.entity.typePublication
relation.isOrgUnitOfPublication8b3335a4-1163-438a-a0e2-921a46e0380d
relation.isOrgUnitOfPublication.latestForDiscovery8b3335a4-1163-438a-a0e2-921a46e0380d
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatubapt

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