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Congenital persistent infection with bovine viral diarrhea virus not observed in piglets

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Canadian Vet Med Assoc

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This study was designed to determine whether congenital persistent infection occurs in piglets from gilts experimentally inoculated with bovine viral diarrhea virus type 2 (BVDV-2). Six pregnant gilts were divided into 2 groups, infected (n = 4), and control (n = 2). The gilts were inoculated at 45 days gestation. Piglets were assessed for 35 days following birth with nasal swab and blood sample collections every 72 hours. Reverse transcriptase-polymerase chain reaction (RT-PCR) tests were performed for direct diagnosis of virus in blood and nasal swabs, and virus neutralization was used for antibody detection. Transplacental transmission of BVDV-2 did not occur. Piglets were born free of the virus and did not shed BVDV during the experimental period.

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Canadian Veterinary Journal-revue Veterinaire Canadienne. Ottawa: Canadian Vet Med Assoc, v. 60, n. 11, p. 1220-1222, 2019.

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