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Crystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A(2) complexed with alpha-tocopherol

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dc.contributor.authordos Santos, J. I.
dc.contributor.authorTakeda, AAS
dc.contributor.authorMarchi-Salvador, D. P.
dc.contributor.authorSoares, A. M.
dc.contributor.authorFontes, MRM
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUNAERP
dc.date.accessioned2014-05-20T13:49:23Z
dc.date.available2014-05-20T13:49:23Z
dc.date.issued2005-11-01
dc.description.abstractBnSP-7 and BnSP-6, two Lys49-phospholipase A(2) isolated from Bothrops neuwiedi pauloensis snake venom, were co-crystallized with a-tocopherol and X-ray diffraction data were collected for both complexes (2.2 and 2.6 angstrom). A new alternative quaternary conformation for these two complexes compared with all other dimeric Lys49-PLA(2) has been observed.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Inst Biociencias, Dept Fis & Biofis, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUNAERP, Dept Biotechnol, Ribeirao Preto, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Inst Biociencias, Dept Fis & Biofis, BR-18618000 Botucatu, SP, Brazil
dc.format.extent819-822
dc.identifierhttp://dx.doi.org/10.2174/0929866054864283
dc.identifier.citationProtein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 12, n. 8, p. 819-822, 2005.
dc.identifier.doi10.2174/0929866054864283
dc.identifier.issn0929-8665
dc.identifier.urihttp://hdl.handle.net/11449/17599
dc.identifier.wosWOS:000232811400017
dc.language.isoeng
dc.publisherBentham Science Publ Ltd
dc.relation.ispartofProtein and Peptide Letters
dc.relation.ispartofjcr1.039
dc.relation.ispartofsjr0,429
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectcrystallizationpt
dc.subjectX-ray crystallographypt
dc.subjectLys49-phospholipase A(2)pt
dc.subjectBothrops neuwiedi venompt
dc.subjectmyotoxitypt
dc.subjectalpha-tocopherolpt
dc.titleCrystallization and preliminary X-ray diffraction studies of two myotoxic Lys49-phospholipases A(2) complexed with alpha-tocopherolen
dc.typeArtigo
dcterms.licensehttp://eurekaselect.com/209
dcterms.rightsHolderBentham Science Publ Ltd
dspace.entity.typePublication
unesp.author.orcid0000-0002-4634-6221[5]
unesp.author.orcid0000-0001-5000-6652[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentFísica e Biofísica - IBBpt

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Botucatu - IBB - Instituto de Biociências