Analysis of metabolic compounds and antitumorigenic effects of Albizia niopoides and Senegalia polyphylla leaves
dc.contributor.author | Cagnin Pereira, Thalissa [UNESP] | |
dc.contributor.author | Cardoso, Luana Pereira [UNESP] | |
dc.contributor.author | da Silva de Paiva, Wesller [UNESP] | |
dc.contributor.author | Santos de Camargos, Liliane [UNESP] | |
dc.contributor.author | Cristina Rodrigues-Lisoni, Flávia [UNESP] | |
dc.contributor.author | Redondo Martins, Aline [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
dc.date.accessioned | 2025-04-29T18:50:23Z | |
dc.date.issued | 2024-01-01 | |
dc.description.abstract | The objective of this study was to quantify metabolic compounds in leaves of A. niopoides and S. polyphylla and to evaluate the antitumor potential of extracts from both species in cervical tumour cells. The physiological analyses performed were quantification of starch, sucrose, phenolic compounds and proteins. An aqueous extract was prepared and added to the SiHa cell line at concentrations of 10, 100 and 1000 μg/mL at 4h, 24h, 48h and 72h. Cell morphology, proliferation and viability were analysed. The species showed a large amount of starch and phenolic compounds. Treatment with the extract of both species caused morphological changes in SiHa cells and exhibited antiproliferative effects at a concentration of 1000 µg/ml. In cell viability test, only A. niopoides showed a significant reduction. The study presented the effects of the species against a cervical cancer cell line, where A. niopoides has already shown to be a promising plant drug. | en |
dc.description.affiliation | Department of Biology and Animal Science Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Faculdade de Engenharia (Feis), SP | |
dc.description.affiliation | Department of Biological Sciences Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Instituto de Biociências Letras e Ciências Exatas (Ibilce), SP | |
dc.description.affiliationUnesp | Department of Biology and Animal Science Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Faculdade de Engenharia (Feis), SP | |
dc.description.affiliationUnesp | Department of Biological Sciences Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Instituto de Biociências Letras e Ciências Exatas (Ibilce), SP | |
dc.identifier | http://dx.doi.org/10.1080/14786419.2024.2331603 | |
dc.identifier.citation | Natural Product Research. | |
dc.identifier.doi | 10.1080/14786419.2024.2331603 | |
dc.identifier.issn | 1478-6427 | |
dc.identifier.issn | 1478-6419 | |
dc.identifier.scopus | 2-s2.0-85188699968 | |
dc.identifier.uri | https://hdl.handle.net/11449/300710 | |
dc.language.iso | eng | |
dc.relation.ispartof | Natural Product Research | |
dc.source | Scopus | |
dc.subject | Antiproliferative effect | |
dc.subject | cell morphology | |
dc.subject | fabaceae | |
dc.subject | phenolic compounds | |
dc.subject | SiHa | |
dc.title | Analysis of metabolic compounds and antitumorigenic effects of Albizia niopoides and Senegalia polyphylla leaves | en |
dc.type | Artigo | pt |
dspace.entity.type | Publication | |
unesp.campus | Universidade Estadual Paulista (UNESP), Faculdade de Engenharia, Ilha Solteira | pt |
unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto | pt |