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Immunomodulatory activities associated with β-glucan derived from Saccharomyces cerevisiae

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dc.contributor.authorPelizon, A. C. [UNESP]
dc.contributor.authorKaneno, Ramon [UNESP]
dc.contributor.authorSoares, A. M V C
dc.contributor.authorMeira, D. A.
dc.contributor.authorSartori, A.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:40Z
dc.date.available2014-05-27T11:21:40Z
dc.date.issued2005-11-16
dc.description.abstractIn this study we investigated the effect of β-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 μg of glucan by i.p. route, were assayed. In vivo β-glucan administration primed spleen cells for a higher production of IL-12 and TNF-α when S. aureus was used as a stimulus. In addition, β-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for β-glucan were observed in this work. © 2005 Institute of Physiology, Academy of Sciences of the Czech Republic.en
dc.description.affiliationDepartment of Microbiology and Immunology Institute de Biosciences State University of Sao Paulo, Sao Paulo
dc.description.affiliationDepartment of Tropical Diseases and Diagnosis by Image Faculty of Medicine State University of Sao Paulo, Sao Paulo
dc.description.affiliationDepartment of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP)
dc.description.affiliationUnespDepartment of Microbiology and Immunology Instituto de Biociências Universidade Estadual Paulista (UNESP)
dc.format.extent557-564
dc.identifierhttp://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm
dc.identifier.citationPhysiological Research, v. 54, n. 5, p. 557-564, 2005.
dc.identifier.file2-s2.0-27644525584.pdf
dc.identifier.issn0862-8408
dc.identifier.lattes8845835550637809
dc.identifier.lattes4977572416129527
dc.identifier.orcid0000-0002-4292-3298
dc.identifier.scopus2-s2.0-27644525584
dc.identifier.urihttp://hdl.handle.net/11449/68495
dc.language.isoeng
dc.relation.ispartofPhysiological Research
dc.relation.ispartofjcr1.324
dc.relation.ispartofsjr0,568
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectβ-glucan
dc.subjectFungicidal activity
dc.subjectIL-12
dc.subjectNK activity
dc.subjectTNF-α
dc.subjectbeta glucan
dc.subjectinterleukin 12
dc.subjecttumor necrosis factor alpha
dc.subjectanimal cell
dc.subjectanimal experiment
dc.subjectcell activity
dc.subjectcontrolled study
dc.subjectcytokine production
dc.subjectdrug effect
dc.subjectfemale
dc.subjectfungicidal activity
dc.subjectimmunomodulation
dc.subjectmouse
dc.subjectnatural killer cell
dc.subjectnonhuman
dc.subjectperitoneum cell
dc.subjectSaccharomyces cerevisiae
dc.subjectspleen cell
dc.subjecttarget cell
dc.subjectAnimals
dc.subjectAntifungal Agents
dc.subjectbeta-Glucans
dc.subjectCytokines
dc.subjectDose-Response Relationship, Drug
dc.subjectFemale
dc.subjectImmunologic Factors
dc.subjectKiller Cells, Natural
dc.subjectMice
dc.subjectMice, Inbred C57BL
dc.subjectParacoccidioides
dc.titleImmunomodulatory activities associated with β-glucan derived from Saccharomyces cerevisiaeen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes4977572416129527[5]
unesp.author.lattes8845835550637809[2]
unesp.author.orcid0000-0003-4557-3331[5]
unesp.author.orcid0000-0002-4292-3298[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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