Acute antibody-mediated rejection of renal transplant associated with cellular crescents: First case report

Acute antibody-mediated rejection is characterized by histological abnormalities such as glomerulitis, capillaritis, or thrombosis associated with presence of C4d and specific anti-donor antibodies. Reports on the association of glomerular injuries with cellular crescents in antibody-mediated rejection are not found in the literature. We report a unique case of antibody-mediated rejection associated with cellular crescents and suggest that such histological abnormality should be considered in the differential diagnosis of acute antibody-mediated rejection. © 2011 Elsevier Inc.

Keywords

mycophenolic acid, prednisone, tacrolimus, thymocyte antibody, acute antibody mediated rejection, acute graft rejection, adult, case report, differential diagnosis, female, focal glomerulonephritis, glomerulitis, human, immunosuppressive treatment, inflammatory infiltrate, kidney graft, priority journal, Female, Graft Rejection, Humans, Kidney Transplantation, Middle Aged