Publicação:
New label free CA125 detection based on gold nanostructured screen-printed electrode

Página do item simplificado
dc.contributor.authorRavalli, A.
dc.contributor.authorPilon Dos Santos, G. [UNESP]
dc.contributor.authorFerroni, M.
dc.contributor.authorFaglia, G.
dc.contributor.authorYamanaka, Hideko [UNESP]
dc.contributor.authorMarrazza, G.
dc.contributor.institutionUniversity of Florence
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCNR-IDASC
dc.date.accessioned2014-05-27T11:27:29Z
dc.date.available2014-05-27T11:27:29Z
dc.date.issued2013-01-01
dc.description.abstractThis paper describes the optimisation and the analytical performances of a label-free impedimetric immunosensor for the detection of tumour marker CA125 based on gold nanoparticles modified screen-printed graphite electrode. Experimental conditions of each step for the developed immunosensor were studied and optimised. The immunosensor response varied linearly (r2 = 0.996) with antigen concentration between 0 and 100 U/mL. The estimated detection limit was 6.7 U/mL. The electrochemical immunosensor allowed unambiguous identification of CA125, while no significant non-specific signal was detected in the case of all negative controls. The analytical usefulness of the impedimetric immunosensor was finally demonstrated analysing serum samples. © 2012 Elsevier B.V. All rights reserved.en
dc.description.affiliationDepartment of Chemistry Ugo Schiff University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence
dc.description.affiliationDepartment of Analytical Chemistry São Paulo State University (UNESP), Rua Prof. Francisco Degni, 14800-900 Araraquara, SP
dc.description.affiliationSENSOR Laboratory - Department of Physics and Chemistry University of Brescia CNR-IDASC, Via Valotti 9, 25133 Brescia
dc.description.affiliationUnespDepartment of Analytical Chemistry São Paulo State University (UNESP), Rua Prof. Francisco Degni, 14800-900 Araraquara, SP
dc.format.extent194-200
dc.identifierhttp://dx.doi.org/10.1016/j.snb.2012.10.017
dc.identifier.citationSensors and Actuators, B: Chemical, v. 179, p. 194-200.
dc.identifier.doi10.1016/j.snb.2012.10.017
dc.identifier.issn0925-4005
dc.identifier.lattes1923726000036625
dc.identifier.scopus2-s2.0-84880921300
dc.identifier.urihttp://hdl.handle.net/11449/74197
dc.identifier.wosWOS:000316588100024
dc.language.isoeng
dc.relation.ispartofSensors and Actuators B: Chemical
dc.relation.ispartofjcr5.667
dc.relation.ispartofsjr1,406
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectCA125
dc.subjectGold nanoparticles
dc.subjectImpedimetric immunosensor
dc.subjectScreen-printed electrode
dc.subjectTumour marker
dc.subjectAnalytical performance
dc.subjectDetection limits
dc.subjectElectrochemical immunosensors
dc.subjectExperimental conditions
dc.subjectGold Nanoparticles
dc.subjectImpedimetric immunosensors
dc.subjectScreen printed electrodes
dc.subjectGold
dc.subjectGraphite electrodes
dc.subjectMetal nanoparticles
dc.subjectTumors
dc.subjectImmunosensors
dc.titleNew label free CA125 detection based on gold nanostructured screen-printed electrodeen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dspace.entity.typePublication
unesp.author.lattes1923726000036625
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.departmentQuímica Analítica - IQARpt

Arquivos

Coleções

Araraquara - IQAR - Instituto de Química