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Microbiological assay for ceftazidime injection

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dc.contributor.authorMoreno, Andreia de Haro
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:34Z
dc.date.available2014-05-20T13:24:34Z
dc.date.issued2007-09-01
dc.description.abstractA simple, sensitive, and specific biodiffusion assay for the! antibacterial ceftazidime was developed using a strain of Staphylococcus epidermidis (ATCC 12228) as the test organism. Ceftazidime was measured in powder for injection at concentrations ranging from 100 to 400 mu g/mL. The calibration graph for ceftazidime was linear (r(2) = 1), and the method validation showed that it was precise (relative standard deviation = 0.415) and accurate. The results obtained by biodiffusion assay were statistically calculated by linear parallel model and by means of regression analysis and were verified using analysis of variance. It was concluded that the microbiological assay is satisfactory for in vitro quantification of the antibacterial activity of ceftazidime in pharmaceuticals.en
dc.description.affiliationUNESP, Fac Ciências Farmaceut, Programa Pos Graduacao Ciências Farmaceut, BR-14801 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Fac Ciências Farmaceut, Programa Pos Graduacao Ciências Farmaceut, BR-14801 Araraquara, SP, Brazil
dc.format.extent1379-1382
dc.identifierhttp://aoac.publisher.ingentaconnect.com/content/aoac/jaoac/2007/00000090/00000005/art00020
dc.identifier.citationJournal of Aoac International. Gaithersburg: Aoac Int, v. 90, n. 5, p. 1379-1382, 2007.
dc.identifier.issn1060-3271
dc.identifier.urihttp://hdl.handle.net/11449/7659
dc.identifier.wosWOS:000249752800020
dc.language.isoeng
dc.publisherAoac Int
dc.relation.ispartofJournal of AOAC International
dc.relation.ispartofjcr1.087
dc.relation.ispartofsjr0,324
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.titleMicrobiological assay for ceftazidime injectionen
dc.typeArtigopt
dcterms.licensehttp://mc.manuscriptcentral.com/societyimages/aoac_jaoac/copyright.pdf
dcterms.rightsHolderAoac Int
dspace.entity.typePublication
relation.isDepartmentOfPublicatione214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isDepartmentOfPublication.latestForDiscoverye214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.orcid0000-0002-0385-340X[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas