Adenocarcinoma de cólon com diferenciação neuro-endócrina e escamosa. Relato de caso.
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A tubular adenocarcinoma of the colon with solid area composed by small cells that was found by immunohistochemistry study using antibody to neuron-specific enolase (NSE) to possess neuroendocrine differentiation is related. In another areas of the tumor were visualized keratinizing squamous cells. The presence of neuro-endocrine and squamous cells features provide further evidence that neoplastic colonic cells have the capacity for multi-directional differentiation. The implications of this combination in relation to theories of tumor origin and differentiation and the prognostic significance of neuro-endocrine cells in malignant neoplasms of the gastrointestinal tract are discussed.
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adenocarcinoma , aged , case report , cell differentiation , colon tumor , female , human , immunohistochemistry , neurosecretion , pathology , squamous cell carcinoma , Adenocarcinoma , Aged , Carcinoma, Squamous Cell , Case Report , Cell Differentiation , Colonic Neoplasms , English Abstract , Female , Human , Immunohistochemistry , Neurosecretory Systems
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Português
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Arquivos de Gastroenterologia, v. 29, n. 2, p. 62-65, 1992.
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