In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
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Date
Advisor
Coadvisor
Graduate program
Undergraduate course
Journal Title
Journal ISSN
Volume Title
Publisher
Faculdade De Odontologia De Bauru - USP
Type
Article
Access right
Acesso aberto
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Abstract
Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.
Description
Keywords
Candida albicans, Cell adhesion, Periodontitis, Virulence factors
Language
English
Citation
Journal of Applied Oral Science. Bauru, SP, Brazil: Faculdade De Odontologia De Bauru - USP, v. 19, n. 4, p. 384-387, 2011.
