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Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla

dc.contributor.authorFontes, Mayana Karoline [UNESP]
dc.contributor.authorRosati, Luigi
dc.contributor.authorDi Lorenzo, Mariana
dc.contributor.authorPereira, Camilo Dias Seabra
dc.contributor.authorMaranho, Luciane Alves
dc.contributor.authorLaforgia, Vincenza
dc.contributor.authorCapaldo, Anna
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of Naples Federico II
dc.contributor.institutionCenter for Studies on Bioinspired Agro-Environmental Technology (BAT Center)
dc.contributor.institutionUniversity of Rio Preto-UNAERP
dc.date.accessioned2023-03-01T21:07:34Z
dc.date.available2023-03-01T21:07:34Z
dc.date.issued2022-07-01
dc.description.abstractPollution is one of the main causes of the loss of biodiversity, currently one of the most important environmental problems. Important sources of aquatic pollution are illicit drugs, whose presence in waters is closely related to human consumption; their psychoactive properties and biological activity suggest potential adverse effects on non-target organisms, such as aquatic biota. In this study, we evaluated the effect of an environmentally relevant concentration of cocaine (20 ng L−1), an illicit drug widely found in surface waters, on the ovaries of Anguilla anguilla, a species critically endangered and able to accumulate cocaine in its tissues following chronic exposure. The following parameters were evaluated: (1) the morphology of the ovaries; (2) the presence and distribution of enzymes involved in oogenesis; (3) serum cortisol, FSH, and LH levels. The eels exposed to cocaine showed a smaller follicular area and a higher percentage of connective tissue than controls (p < 0.05), as well as many previtellogenic oocytes compared with controls having numerous fully vitellogenic and early vitellogenic oocytes. In addition, the presence and location of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase, and P450 aromatase differed in the two groups. Finally, cocaine exposure decreased FSH and LH levels, while it increased cortisol levels. These findings show that even a low environmental concentration of cocaine affects the ovarian morphology and activity of A. anguilla, suggesting a potential impact on reproduction in this species.en
dc.description.affiliationInstitute of Biosciences São Paulo State University “Júlio de Mesquita Filho,”, Litoral Paulista Campus, Praça Infante Dom Henrique s/n
dc.description.affiliationDepartment of Marine Sciences Federal University of São Paulo, Rua Maria Máximo, 168
dc.description.affiliationDepartment of Biology University of Naples Federico II, Via, Cinthia, Edificio 7
dc.description.affiliationCenter for Studies on Bioinspired Agro-Environmental Technology (BAT Center)
dc.description.affiliationMorphofunctional Laboratory University of Rio Preto-UNAERP, Campus Guarujá, Av. D. Pedro I, 3.300 Enseada Guarujá-SP CEP
dc.description.affiliationUnespInstitute of Biosciences São Paulo State University “Júlio de Mesquita Filho,”, Litoral Paulista Campus, Praça Infante Dom Henrique s/n
dc.identifierhttp://dx.doi.org/10.3390/ani12141766
dc.identifier.citationAnimals, v. 12, n. 14, 2022.
dc.identifier.doi10.3390/ani12141766
dc.identifier.issn2076-2615
dc.identifier.scopus2-s2.0-85136162407
dc.identifier.urihttp://hdl.handle.net/11449/241518
dc.language.isoeng
dc.relation.ispartofAnimals
dc.sourceScopus
dc.subjectAnguilla anguilla
dc.subjectcocaine
dc.subjectgonadotropins
dc.subjectoogenesis enzymes
dc.subjectovary
dc.titleAquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguillaen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.orcid0000-0003-2472-0435[2]
unesp.author.orcid0000-0001-8357-8112[4]
unesp.author.orcid0000-0001-9044-2280[7]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, São Vicentept
unesp.departmentCiências Biológicas - IBCLPpt

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