Publicação: Esteroide e triterpenos de espécies de qualea-bioatividade sobre mycobacterium tuberculosis
| dc.contributor.author | Nasser, Ana Lucia Martiniano [UNESP] | |
| dc.contributor.author | Pavan, Fernando Rogério [UNESP] | |
| dc.contributor.author | Boralle, Nivaldo [UNESP] | |
| dc.contributor.author | Zocolo, Guilherme Julião [UNESP] | |
| dc.contributor.author | Dos Santos, Lourdes Campaner [UNESP] | |
| dc.contributor.author | de Marchi, Mary Rosa Rodrigues [UNESP] | |
| dc.contributor.author | Leite, Clarice Queico Fujimura [UNESP] | |
| dc.contributor.author | Vilegas, Wagner [UNESP] | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.date.accessioned | 2022-04-29T09:35:28Z | |
| dc.date.available | 2022-04-29T09:35:28Z | |
| dc.date.issued | 2013-01-01 | |
| dc.description.abstract | The chloroform extract of bark of the tropical tree Qualea parviflora (Vochysiaceae) was fractionated by column chromatography on silica gel, yielding triterpenes (lupeol, lupenone, betulin, epi-betulinic acid and friedelin) and a steroid (β-sitosterol). β-sitosterol, lupenone and lupeol were also identified in Q. grandiflora and Q. multiflora, while friedelin was detected only in Q. Multiflora, by means of gas chromatography-mass spectrometry. The anti-Mycobacterium tuberculosis activity of the chloroform extract and isolated compounds was assayed by MABA and MIC values ranged from 250.0 to 31.2 μg/mL. This study is the first to investigate the chemistry and antitubercular activity of apolar compounds from Qualea species. | en |
| dc.description.affiliation | Instituto de Química, UNESP, Araraquara, São Paulo | |
| dc.description.affiliation | UNESP, Araraquara, São Paulo | |
| dc.description.affiliationUnesp | Instituto de Química, UNESP, Araraquara, São Paulo | |
| dc.description.affiliationUnesp | UNESP, Araraquara, São Paulo | |
| dc.format.extent | 513-517 | |
| dc.identifier.citation | Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 34, n. 4, p. 513-517, 2013. | |
| dc.identifier.issn | 1808-4532 | |
| dc.identifier.scopus | 2-s2.0-84898659908 | |
| dc.identifier.uri | http://hdl.handle.net/11449/232273 | |
| dc.language.iso | eng | |
| dc.language.iso | por | |
| dc.relation.ispartof | Revista de Ciencias Farmaceuticas Basica e Aplicada | |
| dc.source | Scopus | |
| dc.subject | Anti-mycobacterium tuberculosis activity | |
| dc.subject | Qualea species | |
| dc.subject | Triterpenes | |
| dc.title | Esteroide e triterpenos de espécies de qualea-bioatividade sobre mycobacterium tuberculosis | pt |
| dc.title.alternative | Sterol and triterpenes from qualea species: Bioactivity on mycobacterium tuberculosis | en |
| dc.type | Artigo | pt |
| dspace.entity.type | Publication | |
| relation.isDepartmentOfPublication | 5004bcab-94af-4939-b980-091ae9d0a19e | |
| relation.isDepartmentOfPublication.latestForDiscovery | 5004bcab-94af-4939-b980-091ae9d0a19e | |
| unesp.campus | Universidade Estadual Paulista (UNESP), Instituto de Biociências, São Vicente | pt |
| unesp.department | Ciências Biológicas - FCF | pt |
| unesp.department | Ciências Biológicas - IBCLP | pt |