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Is rheumatoid arthritis a risk factor for oral bisphosphonate-induced osteonecrosis of the jaws?

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dc.contributor.authorNeto, Nicolau Conte [UNESP]
dc.contributor.authorBastos, Alliny de Souza [UNESP]
dc.contributor.authorMarcantonio, Rosemary Adriana Chierici [UNESP]
dc.contributor.authorMarcantonio, Elcio [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:31:38Z
dc.date.accessioned2014-05-20T13:45:18Z
dc.date.available2013-09-30T18:31:38Z
dc.date.available2014-05-20T13:45:18Z
dc.date.issued2011-11-01
dc.description.abstractBisphosphonate-related osteonecrosis of the jaws is a relevant side-effect of these drugs that has been generating a great concern through increasing reports, worldwide, of this bone necrosis. Among several BRONJ hypothetical co-factors that could play a role in BRONJ pathogenesis, rheumatoid arthritis (RA) has been included as a relevant risk factor for BRONJ; however, until now the relationship between these diseases has not been fully explained. Thus, the purpose of this paper is to establish hypothetical factors that could link these two diseases, considering mainly inflammatory components and the organism effects of medicines used to treat RA, particularly steroids and methotrexate (MTX). (C) 2011 Elsevier Ltd. All rights reserved.en
dc.description.affiliationUNESP Univ Estadual Paulista, Araraquara Dent Sch, Dept Periodontol, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Araraquara Dent Sch, Dept Periodontol, São Paulo, Brazil
dc.format.extent905-911
dc.identifierhttp://dx.doi.org/10.1016/j.mehy.2011.08.008
dc.identifier.citationMedical Hypotheses. Edinburgh: Churchill Livingstone, v. 77, n. 5, p. 905-911, 2011.
dc.identifier.doi10.1016/j.mehy.2011.08.008
dc.identifier.issn0306-9877
dc.identifier.lattes3534044399884035
dc.identifier.urihttp://hdl.handle.net/11449/15923
dc.identifier.wosWOS:000296684500047
dc.language.isoeng
dc.publisherChurchill Livingstone
dc.relation.ispartofMedical Hypotheses
dc.relation.ispartofjcr1.120
dc.relation.ispartofsjr0,443
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.titleIs rheumatoid arthritis a risk factor for oral bisphosphonate-induced osteonecrosis of the jaws?en
dc.typeArtigopt
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderChurchill Livingstone
dspace.entity.typePublication
relation.isOrgUnitOfPublicationca4c0298-cd82-48ee-a9c8-c97704bac2b0
relation.isOrgUnitOfPublication.latestForDiscoveryca4c0298-cd82-48ee-a9c8-c97704bac2b0
unesp.author.lattes3534044399884035
unesp.author.orcid0000-0002-9660-4524[4]
unesp.author.orcid0000-0002-5052-7439[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
unesp.departmentDiagnóstico e Cirurgia - FOARpt

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Araraquara - FOAR - Faculdade de Odontologia