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Evaluation of Glycemic and Lipid Profile of Offspring of Diabetic Wistar Rats Treated with Malpighia emarginata Juice

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dc.contributor.authorBarbalho, Sandra M.
dc.contributor.authorDamasceno, Débora Cristina [UNESP]
dc.contributor.authorMachado Spada, Ana Paula
dc.contributor.authorPalhares, Mireia
dc.contributor.authorMartuchi, Karla Aparecida
dc.contributor.authorOshiiwa, Marie
dc.contributor.authorSazaki, Viviane
dc.contributor.authorda Silva, Vanessa Sellis
dc.contributor.institutionFac Technol & Foods Marilia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniv Metodista Piracicaba
dc.contributor.institutionFrigorificos Bertin SA
dc.contributor.institutionFaculdade de Tecnologia do Estado de São Paulo (FATEC)
dc.date.accessioned2014-05-20T13:35:53Z
dc.date.available2014-05-20T13:35:53Z
dc.date.issued2011-01-01
dc.description.abstractKnowing that maternal diabetes is related to hyperglycemia and fetal hyperinsulinemia, which affect the lipid metabolism, the aim of this study was to evaluate the effects of Malpighia emarginata (acerola) juice on the glycemic and lipid profile of offspring of diabetic and nondiabetic Wistar rats. The adult offspring of non-diabetic dams and of dams with severe streptozotocin-induced diabetes were divided into groups: G1, offspring (of control dams) treated with water, G2, offspring (of diabetic dams) treated with water, G3, male offspring (of control dams) treated with acerola juice, and G4, male offspring (of diabetic dams) treated with acerola juice. The offspring of diabetic dams treated with acerola juice showed significantly decreased levels of glucose, cholesterol, triglycerides, and increased HDL-c. The use of acerola juice is a potential strategy to aid in the prevention of DM and dyslipidemia and its complications or to act as an auxiliary in the treatment of these diseases.en
dc.description.affiliationFac Technol & Foods Marilia, Med Sch Med Marilia UNIMAR, BR-17525902 Marilia, SP, Brazil
dc.description.affiliationUNESP, Lab Expt Res Gynecol & Obstet, Botucatu Med Sch, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUniv São Paulo, Dept Biochem, Fac UNINOVE, BR-01041000 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, SENAC, BR-01041000 São Paulo, Brazil
dc.description.affiliationUniv Metodista Piracicaba, Dept Nutr, UNIMEP, BR-16400680 Lins, SP, Brazil
dc.description.affiliationFrigorificos Bertin SA, Dept Nutr, BR-16400000 Lins, SP, Brazil
dc.description.affiliationFATEC, Fac Technol & Foods Marilia, BR-17506000 Marilia, SP, Brazil
dc.description.affiliationUnespUNESP, Lab Expt Res Gynecol & Obstet, Botucatu Med Sch, BR-18618000 Botucatu, SP, Brazil
dc.format.extent6
dc.identifierhttp://dx.doi.org/10.1155/2011/173647
dc.identifier.citationExperimental Diabetes Research. New York: Hindawi Publishing Corporation, p. 6, 2011.
dc.identifier.doi10.1155/2011/173647
dc.identifier.fileWOS000289086700001.pdf
dc.identifier.issn1687-5214
dc.identifier.urihttp://hdl.handle.net/11449/12343
dc.identifier.wosWOS:000289086700001
dc.language.isoeng
dc.publisherHindawi Publishing Corporation
dc.relation.ispartofExperimental Diabetes Research
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleEvaluation of Glycemic and Lipid Profile of Offspring of Diabetic Wistar Rats Treated with Malpighia emarginata Juiceen
dc.typeArtigo
dcterms.licensehttp://www.hindawi.com/journals/apm/apc/
dcterms.rightsHolderHindawi Publishing Corporation
dspace.entity.typePublication
unesp.author.orcid0000-0002-7003-9643[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentGinecologia e Obstetrícia - FMBpt

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Botucatu - FMB - Faculdade de Medicina