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Neuron-specific enolase and Tau protein as biomarkers for sepsis-associated delirium: a cross-sectional pilot study

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dc.contributor.authorPinto, Agnes Araújo Sardinha
dc.contributor.authorCarvalho, Maira Mello De
dc.contributor.authorSantos, Juliana Bahia
dc.contributor.authorSilva, Rebeca Souza Da
dc.contributor.authorBarbeiro, Hermes Vieira
dc.contributor.authorGómez, Luz Marina Gómez
dc.contributor.authorMaia, Ian Ward Abdalla
dc.contributor.authorMarchini, Júlio Flávio Meirelles
dc.contributor.authorGarcez, Flávia Barreto
dc.contributor.authorAvelino-silva, Thiago Junqueira
dc.contributor.authorSoler, Lucas De Moraes [UNESP]
dc.contributor.authorMochetti, Matheus Menão
dc.contributor.authorSouza, Heraldo Possolo De
dc.contributor.authorAlencar, Júlio Cesar Garcia
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de Sergipe
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2025-04-29T20:16:58Z
dc.date.issued2025-04-07
dc.description.abstractIn this study, Pinto et al. identified significantly higher levels of neuron-specific enolase and Tau protein in older patients with sepsis-associated delirium in the emergency department, suggesting the potential of these biomarkers as diagnostic tools in this population.en
dc.description.abstract■ Biomarkers of brain injury, such as neuron-specific enolase and Tau proteins, are higher in older patients with sepsis and delirium. ■ Diagnosing sepsis in patients with delirium can be challenging. ■ Early identification of sepsis is key to managing sepsisassociated delirium.en
dc.description.affiliationUniversidade de São Paulo, Faculdade de Medicina
dc.description.affiliationUniversidade de São Paulo, Faculdade de Medicina de Bauru
dc.description.affiliationUniversidade Federal de Sergipe, Hospital Universitário
dc.description.affiliationUniversidade Estadual de São Paulo “Julio de Mesquita Filho”
dc.description.affiliationUnespUniversidade Estadual de São Paulo “Julio de Mesquita Filho”
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2016/14.566-4; 2023/04.997-1
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.31744/einstein_journal/2025AO1244
dc.identifier.citationeinstein (São Paulo). Instituto Israelita de Ensino e Pesquisa Albert Einstein, v. 23, p. -, 2025.
dc.identifier.doi10.31744/einstein_journal/2025AO1244
dc.identifier.fileS1679-45082025000100217.pdf
dc.identifier.issn1679-4508
dc.identifier.issn2317-6385
dc.identifier.scieloS1679-45082025000100217
dc.identifier.urihttps://hdl.handle.net/11449/309870
dc.language.isoeng
dc.publisherInstituto Israelita de Ensino e Pesquisa Albert Einstein
dc.relation.ispartofeinstein (São Paulo)
dc.rights.accessRightsAcesso abertopt
dc.sourceSciELO
dc.subjectBiomarkersen
dc.subjectDeliriumen
dc.subjectEmergency medicineen
dc.subjectNeuroinflammatory diseasesen
dc.subjectSepsisen
dc.titleNeuron-specific enolase and Tau protein as biomarkers for sepsis-associated delirium: a cross-sectional pilot studyen
dc.typeArtigopt
dspace.entity.typePublication
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unesp.author.orcid0009-0007-3342-1599[2]
unesp.author.orcid0009-0004-7428-3661[3]
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unesp.author.orcid0000-0002-8209-4463[5]
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unesp.author.orcid0000-0003-1529-2811[12]
unesp.author.orcid0000-0003-2499-5674[13]
unesp.author.orcid0000-0001-5859-6060[14]

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