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The Use of Virus-like Particles as Immunogens to Treat Infectious Diseases.

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dc.contributor.authorda Silva Sanches, Paulo Ricardo [UNESP]
dc.contributor.authorCilli, Eduardo Maffud [UNESP]
dc.date.accessioned2026-05-12T18:26:05Z
dc.date.issued2025-07-17
dc.description.abstractVirus-like particles (VLPs) represent a promising approach to developing vaccines for infectious diseases. These nanostructures mimic the organization and conformation of native viruses but lack viral genetic material, rendering them non-infectious. VLPs can induce potent immune responses, making them ideal immunogens. This review provides an overview of VLP technology, its application in combating infectious diseases, and its potential to shape future vaccine development. Specific emphasis is placed on current clinical applications, emerging infectious disease targets, and the challenges in optimizing VLP-based immunogens.
dc.description.affiliationSchool of Pharmaceutical Sciences, Laboratory of Molecular Virology, Department of Biological Science, São Paulo State University, UNESP, Brazil.
dc.description.affiliationInstitute of Chemistry, Laboratory of Synthesis and Studies of Biomolecules, Department of Biochemistry and Organic Chemistry, São Paulo State University, UNESP, Brazil.
dc.description.affiliationUnespSchool of Pharmaceutical Sciences, Laboratory of Molecular Virology, Department of Biological Science, São Paulo State University, UNESP, Brazil.
dc.description.affiliationUnespInstitute of Chemistry, Laboratory of Synthesis and Studies of Biomolecules, Department of Biochemistry and Organic Chemistry, São Paulo State University, UNESP, Brazil.
dc.identifierhttps://app.dimensions.ai/details/publication/pub.1190991663
dc.identifier.dimensionspub.1190991663
dc.identifier.doi10.2174/0115680266364554250628134050
dc.identifier.issn1568-0266
dc.identifier.issn1873-4294
dc.identifier.issn15680266
dc.identifier.orcid0000-0002-2898-8191
dc.identifier.orcid0000-0002-4767-0904
dc.identifier.pmid40685730
dc.identifier.urihttps://hdl.handle.net/11449/323762
dc.publisherBentham Science Publishers
dc.relation.ispartofCurrent Topics in Medicinal Chemistry; v. 25
dc.rights.accessRightsAcesso restritopt
dc.rights.sourceRightsclosed
dc.sourceDimensions
dc.titleThe Use of Virus-like Particles as Immunogens to Treat Infectious Diseases.
dc.typeArtigopt
dspace.entity.typePublication
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublicationbc74a1ce-4c4c-4dad-8378-83962d76c4fd
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquara

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Coleções

Araraquara - FCF - Faculdade de Ciências Farmacêuticas
Araraquara - IQAR - Instituto de Química