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In vivo study of novel nanocomposite for prostate cancer treatment

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dc.contributor.authorSilveira, C. P.
dc.contributor.authorPaula, A. J.
dc.contributor.authorApolinário, L. M. [UNESP]
dc.contributor.authorFávaro, W. J. [UNESP]
dc.contributor.authorDurán, N.
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Federal Do Ceará (UFC)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFarmabrasilis R and D Division
dc.date.accessioned2018-12-11T16:41:07Z
dc.date.available2018-12-11T16:41:07Z
dc.date.issued2015-05-26
dc.description.abstractBecause of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporoussilica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer.en
dc.description.affiliationChemistry Institute Universidade Estadual de Campinas (UNICAMP) Campus Universitário Zeferino Vaz, s/n, Cidade Universitária
dc.description.affiliationDepartment of Physics Universidade Federal Do Ceará (UFC), Avenida da Universidade, Benfica, CEP 60020-181, CE
dc.description.affiliationDepartment of Environmental Engineering Universidade Estadual Paulista (UNESP), Avenida Trěs de Março, CEP 18087-180, SP
dc.description.affiliationFarmabrasilis R and D Division
dc.description.affiliationNanobioss Chemistry Institute Universidade Estadual de Campinas (UNICAMP) Campus Universitário Zeferino Vaz, s/n, Cidade Universitária
dc.description.affiliationUnespDepartment of Environmental Engineering Universidade Estadual Paulista (UNESP), Avenida Trěs de Março, CEP 18087-180, SP
dc.identifierhttp://dx.doi.org/10.1088/1742-6596/617/1/012001
dc.identifier.citationJournal of Physics: Conference Series, v. 617, n. 1, 2015.
dc.identifier.doi10.1088/1742-6596/617/1/012001
dc.identifier.file2-s2.0-84958617574.pdf
dc.identifier.issn1742-6596
dc.identifier.issn1742-6588
dc.identifier.scopus2-s2.0-84958617574
dc.identifier.urihttp://hdl.handle.net/11449/168401
dc.language.isoeng
dc.relation.ispartofJournal of Physics: Conference Series
dc.relation.ispartofsjr0,241
dc.relation.ispartofsjr0,241
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleIn vivo study of novel nanocomposite for prostate cancer treatmenten
dc.typeTrabalho apresentado em evento
dspace.entity.typePublication

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