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Chromatographic Methods for the Determination of Rifampicin, Isoniazid, Pyrazinamide, Ethambutol, and Main Metabolites in Biological Samples: A Review

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dc.contributor.authorBrozyna-Heredia, Irena Y.
dc.contributor.authorGanoza-Yupanqui, Mayar Luis
dc.contributor.authorMoreno-Exebio, Luis
dc.contributor.authorDos Santos, Jean Leandro [UNESP]
dc.contributor.institutionUniversidad Nacional de Trujillo
dc.contributor.institutionInstituto Nacional de Salud
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T12:40:03Z
dc.date.available2023-07-29T12:40:03Z
dc.date.issued2022-01-01
dc.description.abstractBioanalytical methods are used to quantify drugs and their metabolites in biological samples in order to determine bioequivalence, perform pharmacokinetic and bioavailability studies, and complete therapeutic drug monitoring. The objective of this review paper is to describe bioanalytical methods based on Liquid Chromatography that are used to quantify antitubercular drugs and their metabolites in different biological samples, utilizing scientific literature from 1992 to 2021.en
dc.description.affiliationLaboratorio de Control de Calidad Facultad de Farmacia y Bioquímica Universidad Nacional de Trujillo
dc.description.affiliationInstituto Nacional de Salud
dc.description.affiliationSchool of Pharmaceutical Sciences São Paulo State University (UNESP)
dc.description.affiliationUnespSchool of Pharmaceutical Sciences São Paulo State University (UNESP)
dc.identifierhttp://dx.doi.org/10.1080/10408347.2022.2150071
dc.identifier.citationCritical Reviews in Analytical Chemistry.
dc.identifier.doi10.1080/10408347.2022.2150071
dc.identifier.issn1547-6510
dc.identifier.issn1040-8347
dc.identifier.scopus2-s2.0-85143067212
dc.identifier.urihttp://hdl.handle.net/11449/246404
dc.language.isoeng
dc.relation.ispartofCritical Reviews in Analytical Chemistry
dc.sourceScopus
dc.subjectBioanalytical
dc.subjectchromatographic method
dc.subjectliquid chromatography
dc.subjectmass spectrometry
dc.subjecttuberculosis drug
dc.titleChromatographic Methods for the Determination of Rifampicin, Isoniazid, Pyrazinamide, Ethambutol, and Main Metabolites in Biological Samples: A Reviewen
dc.typeResenha
dspace.entity.typePublication
unesp.author.orcid0000-0003-1795-6853[1]
unesp.author.orcid0000-0002-6114-1451[2]
unesp.author.orcid0000-0001-8920-1148[3]
unesp.author.orcid0000-0002-2460-2829[4]

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