Repository logo
 

Publication:
Sporothrix schenckii lipid inhibits macrophage phagocytosis: Involvement of nitric oxide and tumour necrosis factor-alpha

Simple item page
dc.contributor.authorCarlos, Iracilda Zeppone [UNESP]
dc.contributor.authorSgarbi, DBG
dc.contributor.authorSantos, G. C.
dc.contributor.authorPlaceres, MCP
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal Fluminense (UFF)
dc.date.accessioned2014-05-20T13:24:24Z
dc.date.available2014-05-20T13:24:24Z
dc.date.issued2003-03-01
dc.description.abstractThe role of cell-wall compounds in the immune response to sporotrichosis is unknown. The effect of cell-wall compounds and exoantigen obtained from Sporothrix schenckii in macrophage/fungus interaction was analysed with respect to nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha). The lipid compound of the cell wall plays an important role in the pathogenesis of this mycosis and was found to inhibit the phagocytic process and to induce high liberation of NO and TNF-alpha in macrophage cultures in the present study. This is a very interesting result because it is the first report about one compound of the fungus S. schenckii that presents this activity.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Fac Ciências Farmaceut Araraquara, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUniv Fed Fluminense, Inst Biomed, Dept Microbiol & Parasitol, Niteroi, RJ, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Fac Ciências Farmaceut Araraquara, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.format.extent214-220
dc.identifierhttp://dx.doi.org/10.1046/j.1365-3083.2003.01175.x
dc.identifier.citationScandinavian Journal of Immunology. Oxford: Blackwell Publishing Ltd, v. 57, n. 3, p. 214-220, 2003.
dc.identifier.doi10.1046/j.1365-3083.2003.01175.x
dc.identifier.fileWOS000181646600002.pdf
dc.identifier.issn0300-9475
dc.identifier.lattes1730146818754269
dc.identifier.urihttp://hdl.handle.net/11449/7545
dc.identifier.wosWOS:000181646600002
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofScandinavian Journal of Immunology
dc.relation.ispartofjcr2.314
dc.relation.ispartofsjr0,891
dc.rights.accessRightsAcesso abertopt
dc.sourceWeb of Science
dc.titleSporothrix schenckii lipid inhibits macrophage phagocytosis: Involvement of nitric oxide and tumour necrosis factor-alphaen
dc.typeArtigopt
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing Ltd
dspace.entity.typePublication
relation.isDepartmentOfPublicationa83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isDepartmentOfPublication.latestForDiscoverya83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes1730146818754269
unesp.author.orcid0000-0002-0084-3468[1]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentAnálises Clínicas - FCFpt

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
WOS000181646600002.pdf
Size:
334.18 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:

Collections

Araraquara - FCF - Faculdade de Ciências Farmacêuticas