Emperipolesis in a Case of B-Cell Lymphoma: A Rare Phenomenon Outside of Rosai-Dorfman Disease
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Elsevier
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We describe a case of a diffuse large B-cell lymphoma with extensive emperipolesis phenomenon. Light microscopy revealed numerous CD68-positive/S-100-negative histiocytes containing viable neoplastic hematopoietic cells in their cytoplasm. Electron microscopy confirmed these findings. In this case, there was no evidence of Rosai-Dorfman disease either clinically or histologically. This report emphasizes that emperipolesis is not restricted to Rosai-Dorfman disease and can be found in other conditions including non-Hodgkin lymphomas. © 2003 Elsevier Inc. All rights reserved.
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Electron microscopy , Emperipolesis , Immunohistochemistry , Lymphoma , Rosai-Dorfman disease , antineoplastic agent , CD68 antigen , protein S 100 , aged , B cell lymphoma , cancer chemotherapy , cancer regression , case report , cell type , cytoplasm , electron microscopy , emperipolesis , hematopoietic cell , histiocyte , histopathology , human , human tissue , immunohistochemistry , male , microscopy , phagocytosis , priority journal , Rosai Dorfman disease , Aged , Antineoplastic Agents , Cytoplasm , Histiocytosis, Sinus , Humans , Immunoenzyme Techniques , Lymph Nodes , Lymphoma, B-Cell , Male , Treatment Outcome , Tumor Markers, Biological
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Annals of Diagnostic Pathology, v. 7, n. 5, p. 310-313, 2003.
