Histopathological and immunohistochemical characterization of a mixed tubule papillary thyroid carcinoma in a Nellore cow
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Brazilian Journal of Veterinary Pathology
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Reports on thyroid carcinomas in bovines are scarce. An 18-year-old Nellore cow was referred to a veterinary hospital due to lateral recumbency lasting one day after falling on irregular terrain. The patient was clinically diagnosed with spinal cord injury. Necropsy and histopathology revealed a thyroid tubule papillary carcinoma. Immunohistochemical analysis revealed discrete positive cells for calcitonin, moderately positive cells for thyroid transcription factor 1 (TTF-1), and strongly positive cells for thyroglobulin in the thyroid gland. Thus, this report describes a case of a mixed tubule papillary carcinoma derived from both medullary and follicular cells in a Nellore cow.
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Brazilian Journal of Veterinary Pathology, v. 17, n. 2, p. 108-111, 2024.
