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Some effects of cimetidine on the reproductive organs of rats

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dc.contributor.authorPereira, O. C. M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T02:43:04Z
dc.date.available2014-05-27T02:43:04Z
dc.date.issued1987-01-01
dc.description.abstract1. The development of genital organs of rats chronically treated with cimetidine showed that the drug may present anti-androgenic activity. 2. This treatment did not alter the sensitivity of vas deferens to noradrenaline, but increased their sensitivity to BaCl2. 3. In the male reproductive system, cimetidine must have peripheral actions apart from the central ones observed after chronic treatment.en
dc.description.affiliationUNESP,BASIC INST MED & AGR BIOL,DEPT PHARMACOL,BR-18600 BOTUCATU,BRAZIL
dc.description.affiliationUnespUNESP,BASIC INST MED & AGR BIOL,DEPT PHARMACOL,BR-18600 BOTUCATU,BRAZIL
dc.format.extent197-199
dc.identifierhttp://dx.doi.org/10.1016/0306-3623(87)90250-3
dc.identifier.citationGeneral Pharmacology: Vascular System, v. 18, n. 2, p. 197-199, 1987.
dc.identifier.doi10.1016/0306-3623(87)90250-3
dc.identifier.issn0306-3623
dc.identifier.scopus2-s2.0-0023130970
dc.identifier.urihttp://hdl.handle.net/11449/130531
dc.identifier.wosWOS:A1987G614900016
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofGeneral Pharmacology: Vascular System
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBarium
dc.subjectCimetidine
dc.subjectCocaine
dc.subjectLenarterenol
dc.subjectNoradrenalin
dc.subjectUnclassified drug
dc.subjectAnimal cell
dc.subjectAnimal experiment
dc.subjectGenital system
dc.subjectIntraperitoneal drug administration
dc.subjectMale genital system
dc.subjectNonhuman
dc.subjectPriority journal
dc.subjectRat
dc.subjectVas deferens
dc.subjectAnimal
dc.subjectBarium
dc.subjectCimetidine
dc.subjectGenitalia, Male
dc.subjectMale
dc.subjectNorepinephrine
dc.subjectOrgan Weight
dc.subjectPituitary Gland
dc.subjectProstate
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.subjectSeminal Vesicles
dc.subjectTestis
dc.subjectVas Deferens
dc.titleSome effects of cimetidine on the reproductive organs of ratsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentFarmacologia - IBBpt

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Botucatu - IBB - Instituto de Biociências