IMMUNOPATHOLOGICAL FINDINGS IN A CAT WITH AURICULAR CHONDRITIS
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Akademiai Kiado Zrt
Akademiai Kiado Zrt.
Akademiai Kiado Zrt.
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At clinical examination, a 5-year-old male domestic short-haired cat exhibited painful swelling and erythema of the pinnae of both ears. Microscopically, the lesions on both pinnae were composed of diffuse granulomatous chondritis with degeneration and necrosis of the pinnal cartilage. Numerous mast cells were also observed within and surrounding the inflammatory lesion. Immunohistochemistry showed a mixed inflammatory infiltrate characterised by the predominance of macrophages (CD68+, MAC 387+ and Lysozyme+), T lymphocytes (CD3+), some B lymphocytes (CD79 alpha+) and neutrophils. Immunopathological characterisation of the lesion showed a granulomatous inflammation profile and suggests that the morphological changes and immunopathogenesis of auricular chondritis in cats presents a similarity with relapsing polychondritis in humans.
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Acta Veterinaria Hungarica. Budapest: Akademiai Kiado Zrt, v. 67, n. 1, p. 81-86, 2019.
