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Experimental infection of inbred BALB/c and A/J mice with Massachusetts and Brazilian strains of infectious bronchitis virus (IBV)

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dc.contributor.authorMartini, Matheus Cavalheiro
dc.contributor.authorGameiro, Jacy
dc.contributor.authorCardoso, Tereza Cristina [UNESP]
dc.contributor.authorCaserta, Leonardo Cardia
dc.contributor.authorGualberto, Ana Carolina
dc.contributor.authorKeid, Lara Borges
dc.contributor.authorOliveira, Tricia Maria Ferreira de Sousa
dc.contributor.authorSantos, Márcia Mercês Aparecida Bianchi dos
dc.contributor.authorArns, Clarice Weis
dc.contributor.authorFerreira, Helena Lage
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Federal de Juiz de Fora (UFJF)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-10-21T13:10:05Z
dc.date.available2015-10-21T13:10:05Z
dc.date.issued2015-07-01
dc.description.abstractThe ability of avian coronaviruses to replicate in mice was investigated to investigate interspecies transmission. Two inbred mouse strains (BALB/c and A/J) with different genetic backgrounds were inoculated with the avian coronavirus strains Mass and BR-I and monitored for at least 10 days. Analysis of viral RNA, histopathological examinations, immunohistochemistry and serology were performed. After virus inoculation, neither clinical signs nor evident gross lesions were observed. Viral RNA, histopathological changes, and viral nucleoprotein were observed in the lung, trachea and sinus of all inoculated mice. Our study demonstrates the importance of elucidating the epidemiology of coronaviruses, including in rodents that are pests in poultry production.en
dc.description.affiliationUniversidade de São Paulo, Departamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos
dc.description.affiliationUniversidade Estadual de Campinas, Laboratório de Virologia Animal, Instituto de Biologia
dc.description.affiliationUniversidade Federal de Juiz de Fora, Instituto de Ciências Biológicas
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Apoio, Produção e Saúde Animal, Faculdade de Medicina Veterinária de Araçatuba
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCNPq: 472840/2011-8
dc.format.extent1785-1790
dc.identifierhttp://link.springer.com/article/10.1007%2Fs00705-015-2443-x
dc.identifier.citationArchives Of Virology. Wien: Springer Wien, v. 160, n. 7, p. 1785-1790, 2015.
dc.identifier.doi10.1007/s00705-015-2443-x
dc.identifier.issn0304-8608
dc.identifier.urihttp://hdl.handle.net/11449/128462
dc.identifier.wosWOS:000356100800018
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofArchives Of Virology
dc.relation.ispartofjcr2.160
dc.relation.ispartofsjr0,973
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectVirusen
dc.subjectMiceen
dc.subjectAvianen
dc.subjectPneumoniaen
dc.titleExperimental infection of inbred BALB/c and A/J mice with Massachusetts and Brazilian strains of infectious bronchitis virus (IBV)en
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária, Araçatubapt
unesp.departmentApoio, Produção e Saúde Animal - FMVApt

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Araçatuba - FMVA - Faculdade de Medicina Veterinária