Publicação:
Evaluation of skin hydration after exposition to the aqueous and hydroalcoholic bases and silicone emulsion

dc.contributor.authorFujimura, Andressa T. [UNESP]
dc.contributor.authorSilva, Márcia da [UNESP]
dc.contributor.authorPolacow, Maria L.O.
dc.contributor.authorLeonardi, Gislaine R.
dc.contributor.authorChorilli, Marlus [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionRodovia do Açúcar, s/n
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:27:32Z
dc.date.available2014-05-27T11:27:32Z
dc.date.issued2013-01-01
dc.description.abstractSeveral dermocosmetic bases even without active substances, can increase the cutaneous hydration, resulting in a beneficial effect to the skin. The evidence and interpretation of possible hydration effect of formulations in the skin can be carried through by means of histopathological and histomorphometrical evaluation, a time that allows the analysis of the epithelial tissue, of dermis and also of the cellular characteristics. The objective of this research was to evaluate the skin hydration after exposition to the aqueous and hydroalcoholic bases and silicone emulsion. Swines had areas submitted to treatments during 15 days with three different formulations (F1 - aqueous gel, F2 - hydroalcoholic gel and F3 - silicone emulsion). By means of histometric and histopathological techniques were gotten the thickness of the epidermis and stratum corneum. Comparison of means was done using ANOVA followed by the Tukey test. The F1 provoked significant increase in the thickness of the epidermis. The formulaton F2 provoked significant reduction in the thickness of the epidermis and stratum corneum. F3 not presented significant difference in this structures. According to the study, the type of base chosen intervenes with the skin hydration.en
dc.description.affiliationSchool of Pharmaceutical Sciences Departament of Drugs and Pharmaceuticals São Paulo State University, UNESP, Rodovia Araraquara/ Jaú Km 1, Araraquara, SP, 14801-902
dc.description.affiliationFaculty of Health Sciences University Methodist of Piracicaba Rodovia do Açúcar, s/n, Piracicaba, SP, 13400-911
dc.description.affiliationInstitute of Environmental Chemistry and Pharmaceuticals Sciences Federal University of São Paulo, UNIFESP, Diadema, SP
dc.description.affiliationUnespSchool of Pharmaceutical Sciences Departament of Drugs and Pharmaceuticals São Paulo State University, UNESP, Rodovia Araraquara/ Jaú Km 1, Araraquara, SP, 14801-902
dc.format.extent9-12
dc.identifierhttp://dx.doi.org/10.7324/JAPS.2013.30103
dc.identifier.citationJournal of Applied Pharmaceutical Science, v. 3, n. 1, p. 9-12, 2013.
dc.identifier.doi10.7324/JAPS.2013.30103
dc.identifier.file2-s2.0-84876061542.pdf
dc.identifier.issn2231-3354
dc.identifier.scopus2-s2.0-84876061542
dc.identifier.urihttp://hdl.handle.net/11449/74317
dc.language.isoeng
dc.relation.ispartofJournal of Applied Pharmaceutical Science
dc.relation.ispartofsjr0,244
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCosmetic bases
dc.subjectHistology
dc.subjectSkin hydration
dc.subjectStratum corneum
dc.titleEvaluation of skin hydration after exposition to the aqueous and hydroalcoholic bases and silicone emulsionen
dc.typeArtigo
dcterms.licensehttp://www.japsonline.com/about-japs.php
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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