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Estudo de metodologia analítica para a determinação do cetoconazol em formulações farmacêuticas

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dc.contributor.authorSantos, Jean Leandrodos [UNESP]
dc.contributor.authorRibeiro, Y. A. [UNESP]
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.authorChin, Chung Man [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:54Z
dc.date.available2014-05-27T11:23:54Z
dc.date.issued2009-05-01
dc.description.abstractKetoconazole is a synthetic broad-spectrum oral and topical antifungal drug derived from imidazole, effective in the treatment of superficial mycoses and systemic infections. In this study we have tested several methods to analyze ketoconazole in various pharmaceutical products containing this drug, employing techniques such as UV and IR spectrophotometry and thermal analysis. The results showed that UV spectrophotometry is a fast, practical and economical method and indicated that other methods, such as IR spectrophotometry and thermal analysis, could be good alternative methods for ketoconazole analysis in certain pharmaceutical forms.en
dc.description.affiliationDepartamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, Rodovia Araraquara/Jau Km1, Araraquara - CEP: 14801-902
dc.description.affiliationUnespDepartamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, Rodovia Araraquara/Jau Km1, Araraquara - CEP: 14801-902
dc.format.extent161-165
dc.identifierhttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/612
dc.identifier.citationRevista de Ciencias Farmaceuticas Basica e Aplicada, v. 30, n. 2, p. 161-165, 2009.
dc.identifier.file2-s2.0-78649874566.pdf
dc.identifier.issn1808-4532
dc.identifier.lattes9734333607975413
dc.identifier.orcid0000-0003-4141-0455
dc.identifier.scopus2-s2.0-78649874566
dc.identifier.urihttp://hdl.handle.net/11449/70999
dc.language.isopor
dc.relation.ispartofRevista de Ciências Farmacêuticas Básica e Aplicada
dc.relation.ispartofsjr0,131
dc.rights.accessRightsAcesso abertopt
dc.sourceScopus
dc.subjectAnalytical methods
dc.subjectAntifungal
dc.subjectKetoconazole
dc.subjectSpectrophotometric analysis
dc.subjectThermal analysis
dc.subjectketoconazole
dc.subjectanalytic method
dc.subjectdrug determination
dc.subjectdrug dosage form
dc.subjectinfrared spectrophotometry
dc.subjectthermal analysis
dc.subjectultraviolet spectrophotometry
dc.titleEstudo de metodologia analítica para a determinação do cetoconazol em formulações farmacêuticaspt
dc.title.alternativeStudy of analytical methodology for ketoconazole determination in pharmaceutical preparationen
dc.typeArtigopt
dcterms.licensehttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/about
dspace.entity.typePublication
relation.isDepartmentOfPublicatione214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isDepartmentOfPublication.latestForDiscoverye214da1b-9929-4ae9-b8fd-655e9bfeda4b
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes9734333607975413[4]
unesp.author.orcid0000-0003-4141-0455[4]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.departmentFármacos e Medicamentos - FCFpt

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Araraquara - FCF - Faculdade de Ciências Farmacêuticas