Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A(2)s from Snake Venoms
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Undergraduate course
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Bentham Science Publ Ltd
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Article
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Acesso restrito
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Abstract
One of the main components of snake venoms are the Asp49-phospholipases A(2), also known as svPLA(2)s. The study of these toxins is a matter of great scientific interest due to their wide variety of biological effects. In this work we present strong evidences found in literature and other aspects which strengthen the importance of quaternary assembly for understanding the activities and molecular evolution of svPLA(2)s.
Description
Keywords
Phospholipase A(2), oligomerization, quaternary conformation, snake venom
Language
English
Citation
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 852-859, 2009.
