Adult still's disease with atypical skin manifestations: A case report

Abstract

Adult Still's Disease (ASD) is a systemic inflammatory disorder of unknown etiology, thought to be triggered by infectious agents in genetically susceptible individuals, resulting in aberrant cytokine production including interleukin (IL) −1, IL-6, AND IL-18. The disease severity varies and may include macrophage activation syndrome (mas), a potentially life-threatening complication. It is associated with seronegative chronic polyarthritis, predominantly affecting young individuals. It is a rare condition with a complex diagnosis due to its overlapping clinical features with more common diseases.