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Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

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Bentham Science Publ Ltd

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Letter

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Abstract

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 angstrom resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered neurotoxin possessing a positively charged AChR-binding site.

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Bucain, Crystal structure, Bungarus candidus, three-finger alpha-neurotoxin

Language

English

Citation

Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 12, p. 1473-1477, 2009.

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Instituto de Biociências, Letras e Ciências Exatas
IBILCE
Campus: São José do Rio Preto


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