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Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

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dc.contributor.authorMurakami, M. T. [UNESP]
dc.contributor.authorKini, R. M.
dc.contributor.authorArni, R. K. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionNatl Univ Singapore
dc.contributor.institutionVirginia Commonwealth Univ
dc.contributor.institutionInstituto Butantan
dc.date.accessioned2014-05-20T14:02:34Z
dc.date.available2014-05-20T14:02:34Z
dc.date.issued2009-01-01
dc.description.abstractBucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 angstrom resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered neurotoxin possessing a positively charged AChR-binding site.en
dc.description.affiliationUNESP, IBILCE, Dept Phys, Ctr Struct & Mol Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil
dc.description.affiliationNatl Univ Singapore, Fac Sci, Dept Biol Sci, Singapore 117548, Singapore
dc.description.affiliationVirginia Commonwealth Univ, Med Coll Virginia, Dept Biochem & Mol Biol, Richmond, VA 23298 USA
dc.description.affiliationInstituto Butantan, CAT CEPID, Ctr Appl Toxinol, São Paulo, Brazil
dc.description.affiliationUnespUNESP, IBILCE, Dept Phys, Ctr Struct & Mol Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 07/5865-1
dc.description.sponsorshipIdCNPq: 501958/2008-8
dc.description.sponsorshipIdCNPq: 553753/2008-8
dc.description.sponsorshipIdCNPq: 307853/2006-3
dc.description.sponsorshipIdCNPq: 471192/2007-4
dc.format.extent1473-1477
dc.identifierhttp://eurekaselect.com/85252/article
dc.identifier.citationProtein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 12, p. 1473-1477, 2009.
dc.identifier.issn0929-8665
dc.identifier.lattes9162508978945887
dc.identifier.orcid0000-0003-2460-1145
dc.identifier.urihttp://hdl.handle.net/11449/22054
dc.identifier.wosWOS:000271620200010
dc.language.isoeng
dc.publisherBentham Science Publ Ltd
dc.relation.ispartofProtein and Peptide Letters
dc.relation.ispartofjcr1.039
dc.relation.ispartofsjr0,429
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectBucainen
dc.subjectCrystal structureen
dc.subjectBungarus candidusen
dc.subjectthree-finger alpha-neurotoxinen
dc.titleCrystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)en
dc.typeCarta
dcterms.licensehttp://www.benthamscience.com/permission.php
dcterms.rightsHolderBentham Science Publ Ltd
dspace.entity.typePublication
unesp.author.lattes9162508978945887[3]
unesp.author.orcid0000-0003-2460-1145[3]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Pretopt
unesp.departmentFísica - IBILCEpt

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São José do Rio Preto - IBILCE - Instituto de Biociências, Letras e Ciências Exatas