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Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species

dc.contributor.authorAlmeida, Fernanda [UNESP]
dc.contributor.authorCorrêa, Marcos [UNESP]
dc.contributor.authorZaera, Ana Melero
dc.contributor.authorGarrigues, Teresa
dc.contributor.authorIsaac, Vera [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Valencia
dc.date.accessioned2022-04-28T19:52:03Z
dc.date.available2022-04-28T19:52:03Z
dc.date.issued2022-06-20
dc.description.abstractAstrocaryum vulgare is an Amazon palm species, popularly known as tucumã. A. vulgare oil has diverse biological purposes, but low solubility in water. Nanoemulsions provide a solution to this problem. This study aimed to evaluate the influence of different surfactants on the development of nanoemulsions. To determine the hydrophilic-lipophilic balance (HLB), the influence of different surfactants on nanoemulsification was determined, the region of nanoemulsion formation on the pseudo-ternary phase diagram was analyzed, nanoemulsions were characterized, and the best candidate was subjected to stability assessment. The HLB was 14, and PPG-5-Ceteth-20 and sorbitan oleate were selected as surfactants. The nanoemulsion had a droplet size of 174.1 nm, a polydispersity index of 0.295, and a zeta potential of 20.7. A. vulgare oil is used in the Amazon for countless pharmaceutical applications. We demonstrate the impact of the chemical structure of surfactants, resulting in the formation of nanoemulsions containing A. vulgare oil.en
dc.description.affiliationSão Paulo State University (Unesp) School of Pharmaceutical Science, São Paulo
dc.description.affiliationUniversity of Valencia Department of Pharmacy and Pharmaceutical Technology
dc.description.affiliationUnespSão Paulo State University (Unesp) School of Pharmaceutical Science, São Paulo
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCNPq: 130611/2019–0
dc.identifierhttp://dx.doi.org/10.1016/j.colsurfa.2022.128721
dc.identifier.citationColloids and Surfaces A: Physicochemical and Engineering Aspects, v. 643.
dc.identifier.doi10.1016/j.colsurfa.2022.128721
dc.identifier.issn1873-4359
dc.identifier.issn0927-7757
dc.identifier.scopus2-s2.0-85126568542
dc.identifier.urihttp://hdl.handle.net/11449/223673
dc.language.isoeng
dc.relation.ispartofColloids and Surfaces A: Physicochemical and Engineering Aspects
dc.sourceScopus
dc.subjectAmazon
dc.subjectLow energy method
dc.subjectNanoemulsion
dc.subjectSurfactants
dc.subjectTucumã
dc.titleInfluence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm speciesen
dc.typeArtigopt
dspace.entity.typePublication
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt

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