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Effect of membrane moiety and magnesium ions on the inhibition of matrix-induced alkaline phosphatase by zinc ions

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dc.contributor.authorClancaglini, Pletro
dc.contributor.authorPlzauro, João M. [UNESP]
dc.contributor.authorCurti, Carlos
dc.contributor.authorTedesco, Antonio C.
dc.contributor.authorLeone, Francisco A.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:53:48Z
dc.date.available2022-04-28T19:53:48Z
dc.date.issued1990-01-01
dc.description.abstract1. 1. The inhibition of matrix-induced alkaline phosphatase by zinc ions is due to the displacement of magnesium ions from its binding site. 2. 2. Binding of magnesium ions to alkaline phosphatase induces conformational changes which activate the enzyme. 3. 3. Binding of zinc ions to alkaline phosphatase induces conformational changes which impair the catalytic action of the enzyme. 4. 4. The inhibition of the enzyme by zinc ions is affected by membrane environment and magnesium ions. © 1990.en
dc.description.affiliationDepartamento de Quimica, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto-USP, 14049 Ribeirão Preto, SP. Brasil [Tel. 634-6255]
dc.description.affiliationDepartamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias-UNESP, 14870 Jaboticabal, SP
dc.description.affiliationDepartamento de Fisica e Química, Faculdade de Ciências Farmaceuticas-USP, 14049 Ribeirão Preto, SP
dc.description.affiliationUnespDepartamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias-UNESP, 14870 Jaboticabal, SP
dc.format.extent747-751
dc.identifierhttp://dx.doi.org/10.1016/0020-711X(90)90010-Z
dc.identifier.citationInternational Journal of Biochemistry, v. 22, n. 7, p. 747-751, 1990.
dc.identifier.dimensionspub.1024453012
dc.identifier.doi10.1016/0020-711X(90)90010-Z
dc.identifier.issn0020-711X
dc.identifier.issn1357-2725
dc.identifier.issn1878-5875
dc.identifier.orcid0000-0003-4515-4057
dc.identifier.orcid0000-0001-8154-5595
dc.identifier.orcid0000-0003-4198-9321
dc.identifier.pmid2401375
dc.identifier.scopus2-s2.0-0025036202
dc.identifier.urihttp://hdl.handle.net/11449/223914
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofInternational Journal of Biochemistry
dc.rights.accessRightsAcesso abertopt
dc.rights.sourceRightsoa_all
dc.rights.sourceRightsgreen
dc.sourceScopus
dc.sourceDimensions
dc.titleEffect of membrane moiety and magnesium ions on the inhibition of matrix-induced alkaline phosphatase by zinc ionsen
dc.typeArtigopt
dspace.entity.typePublication
unesp.departmentTecnologia - FCAVpt

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Jaboticabal - FCAV - Faculdade de Ciências Agrárias e Veterinárias