Publicação: Cordia verbenacea DC. (Boraginaceae): quality control parameters, phytochemical screening and evaluation of anti-Candida activity
| dc.contributor.author | Scardelato, J. A. [UNESP] | |
| dc.contributor.author | Santos, A. G. [UNESP] | |
| dc.contributor.author | Pietro, R. C.L.R. [UNESP] | |
| dc.contributor.author | Sacramento, L. V.S. [UNESP] | |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
| dc.date.accessioned | 2023-07-29T13:44:49Z | |
| dc.date.available | 2023-07-29T13:44:49Z | |
| dc.date.issued | 2016-01-01 | |
| dc.description.abstract | Cordia verbenacea occurs all along the Brazilian coast and it is widely used to treat various inflammatory processes. In the present study we aimed to describe a physical-chemical profile and pharmacognostic vegetal drug as well as to draw a chromatographic profile of the crude extract and its fractions. We have observed the occurrence of secondary metabolites such as flavonoids, terpenes and tannins. The study of anti-Candida activity of extracts indicated the best results for C. glabrata (9.77-36.06 μg.mL-1), intermediate values for C. krusei (312.5-625 μg.mL-1), C. tropicalis (312.5-625μg.mL-1) and high values for C. albicans (1250>2500 μg.mL-1) and C. parapsilosis 625-2500 μg.mL-1). | en |
| dc.description.affiliation | Laboratory of Pharmacognosy Department of Principles of Natural Assets and Toxicology UNESP, SP | |
| dc.description.affiliation | Laboratory of Pharmaceutical Biotechnology Department of Drugs and Medicines UNESP, SP | |
| dc.description.affiliation | Laboratory of Botany Department of Principles of Natural Assets and Toxicology Faculty of Pharmaceutical Sciences UNESP, SP | |
| dc.description.affiliationUnesp | Laboratory of Pharmacognosy Department of Principles of Natural Assets and Toxicology UNESP, SP | |
| dc.description.affiliationUnesp | Laboratory of Pharmaceutical Biotechnology Department of Drugs and Medicines UNESP, SP | |
| dc.description.affiliationUnesp | Laboratory of Botany Department of Principles of Natural Assets and Toxicology Faculty of Pharmaceutical Sciences UNESP, SP | |
| dc.format.extent | 837-843 | |
| dc.identifier | http://dx.doi.org/10.1590/1983-084X/0054 | |
| dc.identifier.citation | Revista Brasileira de Plantas Medicinais, v. 18, n. 4, p. 837-843, 2016. | |
| dc.identifier.doi | 10.1590/1983-084X/0054 | |
| dc.identifier.issn | 1983-084X | |
| dc.identifier.issn | 1516-0572 | |
| dc.identifier.scopus | 2-s2.0-85149416438 | |
| dc.identifier.uri | http://hdl.handle.net/11449/248466 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Revista Brasileira de Plantas Medicinais | |
| dc.source | Scopus | |
| dc.subject | anti-Candida | |
| dc.subject | Cordia | |
| dc.subject | phytochemical | |
| dc.title | Cordia verbenacea DC. (Boraginaceae): quality control parameters, phytochemical screening and evaluation of anti-Candida activity | en |
| dc.title | Cordia verbenacea: parâmetros físico-químicos, fitoquímico da droga vegetal e atividade anti-Candida do extrato hidroetanólico e suas frações | pt |
| dc.type | Artigo | |
| dspace.entity.type | Publication | |
| unesp.department | Princípios Ativos Naturais e Toxicologia - FCF | pt |