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Full-Spectrum Cannabidiol for Treating Chronic Temporomandibular Arthralgia: A Case Report

dc.contributor.authorTanganeli, Joao Paulo Colesanti
dc.contributor.authorTanganeli, Marianna Delle Serre [UNESP]
dc.contributor.authorOliveira, Daniela Fernandes Lobo Molica [UNESP]
dc.contributor.authorFernandes, Ellen Eduarda [UNESP]
dc.contributor.authorRode, Sigmar de Mello [UNESP]
dc.contributor.institutionUniv Nove Julho
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2025-04-29T19:29:28Z
dc.date.issued2023-07-01
dc.description.abstractIntroduction: Temporomandibular disorders (TMDs) are public health problem that can considerably affect quality of life. In particular, chronic situations are a challenge for the involved health teams, as they demand care related to central mechanisms and are not always well understood. Since the discovery of the endocannabinoid system and other systems controlled or influenced by it, many studies have reported positive and promising results. Currently, revisions of legislation regarding the use of cannabis and its derivatives in different parts of the world have allowed us to advance scientifically. The treatment of pain using cannabinoid substances can be of great value for the development of drugs that allow significant advancements in the therapy of patients with pain syndromes, particularly in cases of difficult control. Methods: A case of chronic TMD with several previous interventions was presented who was treated with full-spectrum cannabidiol. Treatment period-started December 13, 2021, continuous use. Results: Excellent results and remarkable improvement yielded in the patient's quality of life. Conclusions: Refractory cases can benefit from the use of medicinal cannabis, but further studies are needed to confirm the efficacy and safety of these drugs to long-term treatment.en
dc.description.affiliationUniv Nove Julho, Dept Orafacial Pain, Postgrad Program, Sao Paulo, Brazil
dc.description.affiliationInst Sci & Technol UNESP, Dept Dent Mat & Prosthodont, Ave Engineer Francisco Jose Longo 777, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationInst Sci & Technol UNESP, Dept Dent Mat & Prosthodont, Sao Jose Dos Campos, Brazil
dc.description.affiliationUnespInst Sci & Technol UNESP, Dept Dent Mat & Prosthodont, Ave Engineer Francisco Jose Longo 777, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationUnespInst Sci & Technol UNESP, Dept Dent Mat & Prosthodont, Sao Jose Dos Campos, Brazil
dc.format.extent60-64
dc.identifierhttp://dx.doi.org/10.1089/imr.2023.0002
dc.identifier.citationIntegrative Medicine Reports. New Rochelle: Mary Ann Liebert, Inc, v. 2, n. 1, p. 60-64, 2023.
dc.identifier.doi10.1089/imr.2023.0002
dc.identifier.urihttps://hdl.handle.net/11449/303386
dc.identifier.wosWOS:001285458300001
dc.language.isoeng
dc.publisherMary Ann Liebert, Inc
dc.relation.ispartofIntegrative Medicine Reports
dc.sourceWeb of Science
dc.subjectCannabis sativa
dc.subjectcannabinoids
dc.subjectendocannabinoids
dc.subjecttemporomandibular disorders
dc.subjectorofacial pain
dc.titleFull-Spectrum Cannabidiol for Treating Chronic Temporomandibular Arthralgia: A Case Reporten
dc.typeArtigopt
dcterms.rightsHolderMary Ann Liebert, Inc
dspace.entity.typePublication
unesp.author.orcid0000-0002-4261-4217[5]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Ciência e Tecnologia, São José dos Campospt

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