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Morphological changes on the hard palatine mucosa of rats (Rattus norvegicus albinus) after chronic alcohol consumption

dc.contributor.authorMartinez, M.
dc.contributor.authorMartinez, F. E.
dc.contributor.authorWatanabe, I
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:47:27Z
dc.date.available2014-05-20T13:47:27Z
dc.date.issued1998-07-01
dc.description.abstractIn order to examine the effects of alcohol on the hard palatine mucosa of rats, sixty adult female rats (Rattus norvegicus albinus) were divided into two experimental groups. The control group received solid diet (Purina rat chow) and tap water ad libitum. The alcoholic group received the same solid diet and was allowed to drink only sugar cane brandy dissolved in 30% Gay Lussac (v/v). At the end of periods of 90, 180 and 270 days of treatment, the animals at estro were sacrificed and the hard palatine mucosa were prepared for TEM and SEM methods. The basal cells of the alcoholic groups (90, 180 and 270 days of treatment) demonstrated some alterations: the intercellular spaces between these cells were higher, presented cytoplasmatic lipid droplets and autolysis. Also, the connective tissue showed intense lipid droplets accumulation in the alcoholic groups. These modifications suggested that chronic alcohol ingestion was able to modify the integrity of the cells in the rat hard palatine mucosa.en
dc.description.affiliationUniv Fed Sao Carlos, Dept Anat & Pathol, BR-13565905 Sao Carlos, SP, Brazil
dc.description.affiliationUNESP, Inst Biosci, Dept Anat, Botucatu, SP, Brazil
dc.description.affiliationUniv São Paulo, Inst Biomed Sci, Dept Anat, São Paulo, Brazil
dc.description.affiliationUnespUNESP, Inst Biosci, Dept Anat, Botucatu, SP, Brazil
dc.format.extent379-384
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/9723198
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology. Bologna: Editrice Compositori Bologna, v. 30, n. 3, p. 379-384, 1998.
dc.identifier.issn1122-9497
dc.identifier.lattes1739564105219382
dc.identifier.urihttp://hdl.handle.net/11449/16886
dc.identifier.wosWOS:000075101100007
dc.language.isoeng
dc.publisherEditrice Compositori Bologna
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectpalatine mucosapt
dc.subjectepitheliumpt
dc.subjectconnective tissuept
dc.subjectalcoholpt
dc.titleMorphological changes on the hard palatine mucosa of rats (Rattus norvegicus albinus) after chronic alcohol consumptionen
dc.typeArtigo
dcterms.rightsHolderEditrice Compositori Bologna
dspace.entity.typePublication
unesp.author.lattes1739564105219382
unesp.author.orcid0000-0002-9317-344X[2]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentAnatomia - IBBpt

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