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Epidemiology and genetics of endemic goiter. II. Genetic aspects

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dc.contributor.authorFreire Maia, A.
dc.contributor.authorVillalba Freire Maia, D.
dc.contributor.authorMorton, N. E.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-26T19:49:38Z
dc.date.available2014-05-26T19:49:38Z
dc.date.issued1982-01-01
dc.description.abstractComplex genetic models and segregation analysis were applied to family data obtained in a hyperendemic goiter area in Brazil. The single locus and Falconer's models did not fit the data. Edward's model showed convergency, but statistical concordance has not been obtained. Although the genetic load model explains statistically the family data, it would be hard to imagine that endemic goiter could be explained by a model where synergism among genetic and environmental factors is not assumed.en
dc.format.extent176-180
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/7106782
dc.identifier.citationHuman Heredity, v. 32, n. 3, p. 176-180, 1982.
dc.identifier.issn0001-5652
dc.identifier.scopus2-s2.0-0019971765
dc.identifier.urihttp://hdl.handle.net/11449/63561
dc.language.isoeng
dc.relation.ispartofHuman Heredity
dc.relation.ispartofjcr0.542
dc.relation.ispartofsjr0,604
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectendemic goiter
dc.subjectendocrine system
dc.subjectenvironment
dc.subjectepidemiology
dc.subjectetiology
dc.subjectgenetic analysis
dc.subjectgenetic load
dc.subjectgoiter
dc.subjectheredity
dc.subjectinheritance
dc.subjectBrazil
dc.subjectChromosome Mapping
dc.subjectEnvironment
dc.subjectFemale
dc.subjectGenetics, Population
dc.subjectGoiter, Endemic
dc.subjectHuman
dc.subjectMale
dc.subjectModels, Genetic
dc.subjectSupport, Non-U.S. Gov't
dc.subjectSupport, U.S. Gov't, P.H.S.
dc.titleEpidemiology and genetics of endemic goiter. II. Genetic aspectsen
dc.typeArtigo
dspace.entity.typePublication

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