Significância clínica de tromboembolismo venoso recorrente

Recurrent venous thromboembolism is a significant problem leading to increased morbidity and mortality. It has a high impact on patients' quality of life and imposes a great financial burden on society. Cumulative recurrence has been reported as 40% at 10 years, while the chance of developing postthrombotic signs and symptoms in the lower extremities almost quadruples when ipsilateral. There is also a higher chance of developing pulmonary hypertension. Important factors for recurrence are unprovoked episodes of deep vein thrombosis, malignancy and older age. The evidence for other factors is controversial. Accurate diagnosis and treatment tailored to the patients' history, thrombotic events and risk factors are necessary to optimize management and prevent recurrence.

Keywords

Anticoagulation, Postthrombotic syndrome, Pulmonary hypertension, Recurrent venous thromboembolism, anticoagulant agent, antivitamin K, heparin, anticoagulant therapy, blood clot lysis, clinical classification, compression garment, computer assisted tomography, deep vein thrombosis, diagnostic accuracy, diagnostic imaging, disease duration, disease severity, echography, follow up, high risk patient, human, lung embolism, medical history, mortality, nuclear magnetic resonance imaging, patient attitude, postthrombosis syndrome, pulmonary hypertension, quality of life, recurrent disease, risk assessment, risk factor, risk reduction, sensitivity and specificity, survival rate, symptomatology, thrombosis prevention, treatment duration, treatment indication