Hepatogenous photosensitization of ruminants by Brachiaria decumbens and Panicum dichotomiflorum in the absence of sporidesmin: Lithogenic saponins may be responsible
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As part of a study of plants involved in crystal-associated hepatogenous photosensitization diseases, samples of Brachiaria decumbens and Panicum dichotomiflorum on which cattle and goats had recently been photosensitized were analyzed. The level of saponins associated with these photosensitization outbreaks were determined by GC-MS. Only low levels of Pithomyces chartarum spores were present on the B decumbens, and all isolates obtained failed to produce sporidesmin.
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sporidesmin analytic method animal experiment animal model cattle controlled study crystal structure goat ingestion liver metabolism nonhuman photosensitization stone formation Animals Cattle Gas Chromatography-Mass Spectrometry Liver Photosensitivity Disorders Plants, Toxic Reference Standards Saponins Sporidesmins Animalia Bos taurus Brachiaria Capra hircus Leptosphaerulina chartarum Panicum dichotomiflorum Pithomyces Urochloa brizantha
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Veterinary and Human Toxicology, v. 38, n. 4, p. 271-274, 1996.
