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Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin

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dc.contributor.authorBorghesan, Alexandre C. [UNESP]
dc.contributor.authorBarbosa, Roberta G. [UNESP]
dc.contributor.authorCerqueira, Nereide F. [UNESP]
dc.contributor.authorTakahira, Regina K. [UNESP]
dc.contributor.authorVulcano, Luiz C. [UNESP]
dc.contributor.authorAlves, Ana Liz G. [UNESP]
dc.contributor.authorWatanabe, Marcos J. [UNESP]
dc.contributor.authorAlonso, Juliana M. [UNESP]
dc.contributor.authorRollo, Hamilton A. [UNESP]
dc.contributor.authorHussni, Carlos A. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:21:20Z
dc.date.available2018-12-11T17:21:20Z
dc.date.issued2018-10-01
dc.description.abstractJugular thrombophlebitis is a major vascular disease in horses and can lead even to death. Heparin is used to inhibit thrombus growth in humans. The aim of this experiment was to evaluate heparin administration in horses with induced thrombophlebitis. Ten animals were subjected to experimental thrombophlebitis and divided into a control group and heparin group (HG). The HG received heparin (150 IU/kg) for 10 days. Coagulation tests, ultrasound, and venography were performed before and after thrombophlebitis induction. Comparing the HG and control group, a break in the growth of the thrombus after the start of administration of the drug and a decrease in the length of the thrombus with the appearance of flow down the sides of the cranial portion of the thrombus were observed. However, after discontinuation of heparin, fast daily growth of the thrombus and decreased blood flow to the side were observed.en
dc.description.affiliationDepartment of Veterinary Surgery and Anesthesiology School of Veterinary Medicine and Animal Science São Paulo State University (Unesp)
dc.description.affiliationDepartment of Surgery Medical School São Paulo State University (Unesp)
dc.description.affiliationUnespDepartment of Veterinary Surgery and Anesthesiology School of Veterinary Medicine and Animal Science São Paulo State University (Unesp)
dc.description.affiliationUnespDepartment of Surgery Medical School São Paulo State University (Unesp)
dc.format.extent59-65
dc.identifierhttp://dx.doi.org/10.1016/j.jevs.2018.06.010
dc.identifier.citationJournal of Equine Veterinary Science, v. 69, p. 59-65.
dc.identifier.doi10.1016/j.jevs.2018.06.010
dc.identifier.file2-s2.0-85049508259.pdf
dc.identifier.issn0737-0806
dc.identifier.scopus2-s2.0-85049508259
dc.identifier.urihttp://hdl.handle.net/11449/176555
dc.language.isoeng
dc.relation.ispartofJournal of Equine Veterinary Science
dc.relation.ispartofsjr0,390
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectActivated partial thromboplastin time
dc.subjectHorses
dc.subjectThrombosis
dc.subjectUltrasound
dc.subjectVenography
dc.titleEvaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparinen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes7773733250141398[6]
unesp.author.lattes6020984937849801[10]
unesp.author.orcid0000-0001-9092-7819[6]
unesp.author.orcid0000-0001-5421-2904[10]
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
unesp.departmentCirurgia e Anestesiologia Veterinária - FMVZpt

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Botucatu - FMVZ - Faculdade de Medicina Veterinária e Zootecnia