Publicação: Relation of shear stress and K L a on bikaverin production by Fusarium oxysporum CCT7620 in a bioreactor
Carregando...
Data
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Resumo
This study involved evaluating the effects of rotational impeller speed agitation (N) and specific air flow rate (Фair) on bikaverin production and on the growth of Fusarium oxysporum employing 11 bench-scale bioreactor assays. The results showed that the maximum bikaverin production (close to 300 mg L−1) was achieved after 48 h of fermentation in rice medium (20 g L−1 milled rice in water) at 28 °C with a volumetric oxygen transfer coefficient (KLa) and shear stress values of approximately 20 h−1 and 17 N m−2, respectively. We reached this combination of parameters using an N of 340 rpm and Фair of 0.935 vvm. These KLa and shear stress values can be used as references when upscaling this process. Thus, this study was important to demonstrate how the main parameters in bioreactors affect bikaverin production and it presented important indications for upscaling this bioprocess.
Descrição
Palavras-chave
Blue pigment, Optimization, Scale-up, Shear stress, Volumetric oxygen transfer coefficient (KLa)
Idioma
Inglês
Como citar
Bioprocess and Biosystems Engineering.
