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COX-2 and TGF-β expression in proliferative disorders of canine prostate

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Abstract

COX-2 and TGF-β expression was determined in order to correlate non-neoplastic lesions, preneoplastic lesions and carcinoma in the prostate of dogs. The results show that neoplastic and preneoplastic lesions express more COX-2 and TGF-β when compared to carcinomas, which suggests these proteins may cooperate in the process of prostate tumorigenesis.

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English

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Brazilian Journal of Veterinary Pathology, v. 3, n. 1, p. 31-36, 2010.

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